Q14643 | ITPR1_HUMAN | Inositol 1,4,5-trisphosphate receptor type 1 (ITPR1)

Helixβ‑strandTurn secondary structure

Pfam Domain Table

AccessionDomainRangeColor
PF00520Ion_trans2363–2608
PF01365RYDR_ITPR474–670
PF01365RYDR_ITPR1204–1352
PF02815MIR233–432
PF08454RIH_assoc1971–2077
PF08709Ins145_P3_rec5–229

 3D structures mapped by conservation among orthologs


 [ Alpha Fold Model ] (go)



 Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL279107 IC50 = 300.0 nM 420.09 O=P(O)(O)O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(=O)(O)O)[C@H](OP(=O)(O)O)[C@H]1O Homo sapiens CHEMBL750780 cell-based format