Q14573 | ITPR3_HUMAN | Inositol 1,4,5-trisphosphate receptor type 3 (ITPR3)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
Accession | Domain | Range | Color |
---|---|---|---|
PF00520 | Ion_trans | 2239–2527 | |
PF01365 | RYDR_ITPR | 474–670 | |
PF01365 | RYDR_ITPR | 1188–1327 | |
PF02815 | MIR | 234–431 | |
PF08454 | RIH_assoc | 1867–1973 | |
PF08709 | Ins145_P3_rec | 4–229 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
---|---|---|---|---|---|---|---|---|---|---|
CHEMBL23552 | IC50 | = | 2.9 | nM | 500.07 | O=P(O)(O)O[C@H]1[C@H](O)[C@@H](OP(=O)(O)O)[C@H](OP(=O)(O)O)[C@@H](OP(=O)(O)O)[C@H]1O | Homo sapiens | CHEMBL697185 | tissue-based format | |
CHEMBL283791 | IC50 | = | 6.1 | nM | 420.09 | O=P(O)(O)O[C@H]1[C@H](OP(=O)(O)O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1OP(=O)(O)O | Homo sapiens | CHEMBL697185 | tissue-based format | |
CHEMBL281132 | IC50 | = | 44.0 | nM | 434.12 | C[C@]1(OP(=O)(O)O)[C@H](OP(=O)(O)O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1OP(=O)(O)O | Homo sapiens | CHEMBL697185 | tissue-based format | |
CHEMBL282059 | IC50 | = | 430.0 | nM | 500.07 | O=P(O)(O)O[C@@H]1[C@@H](OP(=O)(O)O)[C@H](OP(=O)(O)O)[C@@H](O)[C@@H](O)[C@H]1OP(=O)(O)O | Homo sapiens | CHEMBL697185 | tissue-based format | |
CHEMBL23050 | IC50 | = | 620.0 | nM | 500.07 | O=P(O)(O)O[C@H]1[C@H](OP(=O)(O)O)[C@@H](OP(=O)(O)O)[C@@H](O)[C@@H](O)[C@@H]1OP(=O)(O)O | Homo sapiens | CHEMBL697185 | tissue-based format |