Q14004 | CDK13_HUMAN | Cyclin-dependent kinase 13 (CDK13)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 707~997 |
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4797074 |  |
IC50 | = | 0.9 | nM | 363.42 | C=CC(=O)N1CC=C(c2ccc(CC(=O)Nc3cc(C4CC4)[nH]n3)cn2)C1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4784925 |  |
IC50 | = | 3.0 | nM | 391.48 | C/C=C/C(=O)N1CCC=C(c2ccc(CC(=O)Nc3cc(C4CC4)[nH]n3)cn2)C1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4778361 |  |
IC50 | = | 3.0 | nM | 391.48 | C=CC(=O)N1CC=C(c2ccc(C(C)C(=O)Nc3cc(C4CC4)[nH]n3)cn2)CC1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4760738 |  |
IC50 | = | 3.8 | nM | 415.5 | C=CC(=O)NCc1ccc(-c2ccc([C@H](C)C(=O)Nc3cc(C4CC4)[nH]n3)cc2)cn1 | Homo sapiens | CHEMBL4739836 | single protein format |
| CHEMBL4759298 |  |
IC50 | = | 4.0 | nM | 416.49 | C=CC(=O)NCc1ccc(-c2ccc(C(C)C(=O)Nc3cc(C4CC4)[nH]n3)cn2)cn1 | Homo sapiens | CHEMBL4739836 | single protein format |
| CHEMBL4791883 |  |
IC50 | = | 4.0 | nM | 377.45 | C=CC(=O)N1CCC=C(c2ccc(CC(=O)Nc3cc(C4CC4)[nH]n3)cn2)C1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4847754 |  |
IC50 | = | 4.0 | nM | 467.44 | Cc1cc(-n2cnc3c(NCc4nc5c(F)c(F)ccc5[nH]4)nc(N4CCOCC4)nc32)no1 | Homo sapiens | CHEMBL4806300 | single protein format |
| CHEMBL4788447 |  |
IC50 | = | 4.3 | nM | 390.49 | C=CC(=O)N1CCC=C(c2ccc([C@H](C)C(=O)Nc3cc(C4CC4)[nH]n3)cc2)C1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4786926 |  |
IC50 | = | 5.0 | nM | 389.46 | CC#CC(=O)N1CCC=C(c2ccc(CC(=O)Nc3cc(C4CC4)[nH]n3)cn2)C1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4852083 |  |
IC50 | = | 5.0 | nM | 466.46 | Cn1cc(-n2cnc3c(NCc4nc5c(F)c(F)ccc5[nH]4)nc(N4CCOCC4)nc32)cn1 | Homo sapiens | CHEMBL4806300 | single protein format |
| CHEMBL4777358 |  |
IC50 | = | 5.0 | nM | 390.49 | C=CC(=O)N1CC=C(c2ccc([C@H](C)C(=O)Nc3cc(C4CC4)[nH]n3)cc2)CC1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4877117 |  |
IC50 | = | 5.0 | nM | 499.37 | Cn1cc(-n2cnc3c(NCc4nc5cc(Cl)c(Cl)cc5[nH]4)nc(N4CCOCC4)nc32)cn1 | Homo sapiens | CHEMBL4806300 | single protein format |
| CHEMBL4792293 |  |
IC50 | = | 5.8 | nM | 408.48 | C=CC(=O)N1CC=C(c2ccc(C(C)C(=O)Nc3cc(C4CC4)[nH]n3)cc2F)CC1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4776295 |  |
IC50 | = | 6.0 | nM | 379.46 | C=CC(=O)N1CCC(c2ccc(C(C)C(=O)Nc3cc(C4CC4)[nH]n3)cn2)C1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4781207 |  |
IC50 | = | 6.0 | nM | 391.48 | C=CC(=O)N1CCC=C(c2ccc(C(C)C(=O)Nc3cc(C4CC4)[nH]n3)cn2)C1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4784656 |  |
IC50 | = | 7.0 | nM | 389.46 | C#CC(=O)N1CC=C(c2ccc(C(C)C(=O)Nc3cc(C4CC4)[nH]n3)cn2)CC1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL4800122 |  |
IC50 | = | 7.0 | nM | 392.5 | C=CC(=O)N1CCC(c2ccc([C@H](C)C(=O)Nc3cc(C4CC4)[nH]n3)cc2)CC1 | Homo sapiens | CHEMBL4742551 | single protein format |
| CHEMBL5193291 |  |
IC50 | = | 10.0 | nM | 532.65 | Cn1cc(-c2ccc(N(C(=O)NCc3ccccc3)C3CCC(Nc4ccc(C#N)cn4)CC3)cc2)ccc1=O | Homo sapiens | CHEMBL5109319 | single protein format |
| CHEMBL4211454 |  |
IC50 | = | 10.0 | nM | 480.45 | Fc1cccc(-n2cnc3c(NCc4nc5c(F)c(F)ccc5[nH]4)nc(N4CCOCC4)nc32)c1 | Homo sapiens | CHEMBL4806300 | single protein format |
| CHEMBL4799777 |  |
IC50 | = | 10.0 | nM | 391.48 | C=C(C)C(=O)N1CCC=C(c2ccc(CC(=O)Nc3cc(C4CC4)[nH]n3)cn2)C1 | Homo sapiens | CHEMBL4742551 | single protein format |