3D structures mapped by conservation among orthologs

[ Domain: "beta-beta-alpha zinc fingers" // zf-C2H2_18 ]

 PyMOL session

[ Domain: "beta-beta-alpha zinc fingers" // zf-C2H2_12 ]

 PyMOL session

 [ Alpha Fold Model ] (go)

 Known binders annotated in ChEMBL

 IC50 CSV

Only the first 20 rows are shown.

molecule_chembl_id	structure	assay_type	relation	value	unit	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL4462423		IC50	=	54.0	nM	384.89	CN(C(=O)CNC(=O)/C=C/c1cccc(Cl)c1)C1CCS(=O)(=O)CC1	Homo sapiens	CHEMBL4418633	cell-based format
CHEMBL4544912		IC50	=	72.0	nM	398.91	CCN(C(=O)CNC(=O)/C=C/c1cccc(Cl)c1)C1CCS(=O)(=O)CC1	Homo sapiens	CHEMBL4418633	cell-based format
CHEMBL1330145		IC50	=	270.0	nM	382.39	CN(C(=O)COC(=O)/C=C/c1cccc([N+](=O)[O-])c1)C1CCS(=O)(=O)C1	Homo sapiens	CHEMBL4418633	cell-based format