Q13557 | KCC2D_HUMAN | Calcium/calmodulin-dependent protein kinase type II subunit delta (CAMK2D)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 14~272 | |
| PF08332 | CaMKII_AD - Calcium/calmodulin dependent protein kinase II association domain | 346~473 |
3D structures mapped by conservation among orthologs
[ Domain: "NTF2-like" // DUF4440 ]
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 0.0311 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328335 | single protein format |
| CHEMBL4218769 |  |
IC50 | = | 0.05 | nM | 463.61 | CCN(CC)[C@@H](C)CNC(=O)c1cc(NC)nc(-c2cnn3ccc(-c4cccs4)nc23)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4208018 |  |
IC50 | = | 0.06 | nM | 519.68 | CCN(CC)[C@@H](C)CNC(=O)c1cc(-c2cnn3ccc(-c4cccs4)nc23)nc(N2CC[C@@H](O)C2)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4215817 |  |
IC50 | = | 0.07 | nM | 519.68 | CCN(CC)[C@@H](C)CNC(=O)c1cc(-c2cnn3ccc(-c4cccs4)nc23)nc(N2CC[C@H](O)C2)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4218245 |  |
IC50 | = | 0.08 | nM | 507.66 | CCN(CC)[C@@H](C)CNC(=O)c1cc(NCCOC)nc(-c2cnn3ccc(-c4cccs4)nc23)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4217261 |  |
IC50 | = | 0.09 | nM | 434.57 | CCN(CC)[C@@H](C)CNC(=O)c1ccnc(-c2cnn3ccc(-c4cccs4)nc23)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4215300 |  |
IC50 | = | 0.1 | nM | 519.68 | CCN(CC)[C@@H](C)CNC(=O)c1cc(-c2cnn3ccc(-c4cccs4)nc23)nc(N2CC(OC)C2)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4206514 |  |
IC50 | = | 0.1 | nM | 493.64 | CCN(CC)[C@@H](C)CNC(=O)c1cc(NCCO)nc(-c2cnn3ccc(-c4cccs4)nc23)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4210359 |  |
IC50 | = | 0.1 | nM | 505.65 | CCN(CC)[C@@H](C)CNC(=O)c1cc(-c2cnn3ccc(-c4cccs4)nc23)nc(N2CC(O)C2)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4209816 |  |
IC50 | = | 0.22 | nM | 533.7 | CCN(CC)[C@@H](C)CNC(=O)c1cc(-c2cnn3ccc(-c4cccs4)nc23)nc(N2CCC(O)CC2)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4213838 |  |
IC50 | = | 0.23 | nM | 477.64 | CCN(CC)[C@@H](C)CNC(=O)c1cc(-c2cnn3ccc(-c4cccs4)nc23)nc(N(C)C)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4210881 |  |
IC50 | = | 0.28 | nM | 508.65 | CCN(CC)[C@@H](C)CNC(=O)c1cc(OCCOC)nc(-c2cnn3ccc(-c4cccs4)nc23)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4205997 |  |
IC50 | = | 0.3 | nM | 519.68 | CCN(CC)[C@@H](C)CNC(=O)c1cc(-c2cnn3ccc(-c4cccs4)nc23)nc(N2CCOCC2)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4209443 |  |
IC50 | = | 0.92 | nM | 462.62 | CCc1cc(C(=O)NC[C@H](C)N(CC)CC)cc(-c2cnn3ccc(-c4cccs4)nc23)n1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4205708 |  |
IC50 | = | 1.6 | nM | 420.54 | CCN(CC)CCNC(=O)c1ccnc(-c2cnn3ccc(-c4cccs4)nc23)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL3699625 |  |
IC50 | = | 2.0 | nM | 522.61 | CCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3ccc(N4CCC(N5CCOCC5)CC4)cc3OC)nc21 | Homo sapiens | CHEMBL3706051 | single protein format |
| CHEMBL4211430 |  |
IC50 | = | 2.17 | nM | 434.57 | CCN(CC)C[C@H](C)NC(=O)c1ccnc(-c2cnn3ccc(-c4cccs4)nc23)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4213305 |  |
IC50 | = | 3.3 | nM | 459.58 | CCN(CC)CCNC(=O)c1cc(-c2cnn3ccc(-c4cccs4)nc23)c2nccn2c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4209840 |  |
IC50 | = | 3.4 | nM | 432.55 | CCN1CCC[C@H]1CNC(=O)c1ccnc(-c2cnn3ccc(-c4cccs4)nc23)c1 | Homo sapiens | CHEMBL4184342 | assay format |
| CHEMBL4210568 |  |
IC50 | = | 3.5 | nM | 419.55 | CCN(CC)CCNC(=O)c1cccc(-c2cnn3ccc(-c4cccs4)nc23)c1 | Homo sapiens | CHEMBL4184342 | assay format |