Q13443 | ADAM9_HUMAN | Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00200 | Disintegrin - Disintegrin | 423~496 | |
| PF01421 | Reprolysin - Reprolysin (M12B) family zinc metalloprotease | 212~406 | |
| PF01562 | Pep_M12B_propep - Reprolysin family propeptide | 44~121 | |
| PF08516 | ADAM_CR - ADAM cysteine-rich | 501~615 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL19611 |  |
IC50 | = | 1.0 | nM | 388.47 | CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CC(=O)NO)CC(C)C | Homo sapiens | CHEMBL829521 | single protein format |
| CHEMBL353536 |  |
IC50 | = | 70.0 | nM | 448.46 | CCOCCOc1ccc(P(=O)(OCC)N2Cc3ccccc3CC2C(=O)NO)cc1 | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL170315 |  |
IC50 | = | 70.0 | nM | 376.35 | COc1ccc(P(=O)(OC)N2Cc3ccccc3CC2C(=O)NO)cc1 | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL206815 |  |
IC50 | = | 85.0 | nM | 414.51 | CC1(C)SCCN(S(=O)(=O)c2ccc(OCC#CCO)cc2)[C@H]1C(=O)NO | Homo sapiens | CHEMBL3888014 | single protein format |
| CHEMBL3392650 |  |
IC50 | = | 85.0 | nM | 414.51 | CC1(C)SCCN(S(=O)(=O)c2ccc(OCC#CCO)cc2)C1C(=O)NO | Homo sapiens | CHEMBL3707626 | single protein format |
| CHEMBL173027 |  |
IC50 | = | 180.0 | nM | 467.46 | COc1ccc(P(=O)(OCCc2ccccn2)N2Cc3ccccc3CC2C(=O)NO)cc1 | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL171962 |  |
IC50 | = | 190.0 | nM | 405.39 | CCOP(=O)(c1ccc(OC)cc1)N1Cc2cc(N)ccc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL366478 |  |
IC50 | = | 230.0 | nM | 390.38 | CCO[P@@](=O)(c1ccc(OC)cc1)N1Cc2ccccc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL355797 |  |
IC50 | = | 260.0 | nM | 452.45 | CCOP(=O)(c1ccc(Oc2ccccc2)cc1)N1Cc2ccccc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL172885 |  |
IC50 | = | 300.0 | nM | 378.34 | CCOP(=O)(c1ccc(F)cc1)N1Cc2ccccc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL172548 |  |
IC50 | = | 370.0 | nM | 360.35 | CCOP(=O)(c1ccccc1)N1Cc2ccccc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL173235 |  |
IC50 | = | 430.0 | nM | 477.45 | CCOP(=O)(c1ccc(OC)cc1)N1CCN(C(=O)OCc2ccccc2)CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL368857 |  |
IC50 | = | 510.0 | nM | 434.43 | CCOCCOP(=O)(c1ccc(OC)cc1)N1Cc2ccccc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL173316 |  |
IC50 | = | 520.0 | nM | 396.41 | CCOP(=O)(c1ccc(OC)cc1)N1Cc2ccsc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL177072 |  |
IC50 | = | 560.0 | nM | 392.35 | CCOP(=O)(c1ccc(OC)cc1)N1Cc2nccnc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL436049 |  |
IC50 | = | 660.0 | nM | 375.37 | CCOP(=O)(c1ccc(N)cc1)N1Cc2ccccc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL173686 |  |
IC50 | = | 660.0 | nM | 453.44 | CCOP(=O)(c1ccc(Oc2ccncc2)cc1)N1Cc2ccccc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL175164 |  |
IC50 | = | 700.0 | nM | 388.4 | CCOP(=O)(CCc1ccccc1)N1Cc2ccccc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL172249 |  |
IC50 | = | 800.0 | nM | 429.41 | CCOP(=O)(c1ccc(OC)cc1)N1Cc2[nH]c3ccccc3c2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |
| CHEMBL368205 |  |
IC50 | = | 810.0 | nM | 418.43 | CCCCOP(=O)(c1ccc(OC)cc1)N1Cc2ccccc2CC1C(=O)NO | Homo sapiens | CHEMBL675240 | single protein format |