Q13332 | PTPRS_HUMAN | Receptor-type tyrosine-protein phosphatase S (PTPRS)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00041 | fn3 | 334–419 | |
| PF00041 | fn3 | 428–518 | |
| PF00041 | fn3 | 527–610 | |
| PF00041 | fn3 | 621–713 | |
| PF00041 | fn3 | 723–823 | |
| PF00041 | fn3 | 838–919 | |
| PF00041 | fn3 | 932–1025 | |
| PF00041 | fn3 | 1036–1100 | |
| PF00102 | Y_phosphatase | 1416–1647 | |
| PF00102 | Y_phosphatase | 1705–1938 | |
| PF07679 | I-set | 33–124 | |
| PF13927 | Ig_3 | 135–220 | |
| PF13927 | Ig_3 | 245–313 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // fn3 ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set ]
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_2 ]
[ Domain: "(Phosphotyrosine protein) phosphatases II" // Y_phosphatase ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1438439 |  |
IC50 | = | 500.0 | nM | 318.24 | O=c1c(-c2cc(O)c(O)c(O)c2)coc2cc(O)c(O)c(O)c12 | Homo sapiens | CHEMBL3744704 | single protein format |
| CHEMBL55415 |  |
IC50 | = | 600.0 | nM | 286.24 | O=c1cc(-c2ccc(O)cc2)oc2cc(O)c(O)c(O)c12 | Homo sapiens | CHEMBL3744704 | single protein format |
| CHEMBL3739950 |  |
IC50 | = | 800.0 | nM | 260.2 | O=c1cc(-c2ccco2)oc2cc(O)c(O)c(O)c12 | Homo sapiens | CHEMBL3744704 | single protein format |
| CHEMBL3740878 |  |
IC50 | = | 900.0 | nM | 260.2 | O=c1cc(-c2ccoc2)oc2cc(O)c(O)c(O)c12 | Homo sapiens | CHEMBL3744704 | single protein format |