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Q13332 | PTPRS_HUMAN | Receptor-type tyrosine-protein phosphatase S (PTPRS)

Pfam Domain Table

Accession	Domain	Range	Color
PF00041	fn3 - Fibronectin type III domain	334~419
PF00041	fn3 - Fibronectin type III domain	428~518
PF00041	fn3 - Fibronectin type III domain	527~610
PF00041	fn3 - Fibronectin type III domain	621~713
PF00041	fn3 - Fibronectin type III domain	723~823
PF00041	fn3 - Fibronectin type III domain	838~919
PF00041	fn3 - Fibronectin type III domain	932~1025
PF00041	fn3 - Fibronectin type III domain	1036~1100
PF00102	Y_phosphatase - Protein-tyrosine phosphatase	1416~1647
PF00102	Y_phosphatase - Protein-tyrosine phosphatase	1705~1938
PF07679	I-set - Immunoglobulin I-set domain	33~124
PF13927	Ig_3 - Immunoglobulin domain	135~220
PF13927	Ig_3 - Immunoglobulin domain	245~313

3D structures mapped by conservation among orthologs

[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // fn3 ]

4PBX

[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set ]

[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // I-set_2 ]

[ Domain: "(Phosphotyrosine protein) phosphatases II" // Y_phosphatase ]

2FH7
4BPC

[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

Only the first 20 rows are shown.

molecule_chembl_id	structure	assay_type	relation	value	unit	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL1438439		IC50	=	500.0	nM	318.24	O=c1c(-c2cc(O)c(O)c(O)c2)coc2cc(O)c(O)c(O)c12	Homo sapiens	CHEMBL3744704	single protein format
CHEMBL55415		IC50	=	600.0	nM	286.24	O=c1cc(-c2ccc(O)cc2)oc2cc(O)c(O)c(O)c12	Homo sapiens	CHEMBL3744704	single protein format
CHEMBL3739950		IC50	=	800.0	nM	260.2	O=c1cc(-c2ccco2)oc2cc(O)c(O)c(O)c12	Homo sapiens	CHEMBL3744704	single protein format
CHEMBL3740878		IC50	=	900.0	nM	260.2	O=c1cc(-c2ccoc2)oc2cc(O)c(O)c(O)c12	Homo sapiens	CHEMBL3744704	single protein format