Q13285 | STF1_HUMAN | Steroidogenic factor 1 (NR5A1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00104 | Hormone_recep - Ligand-binding domain of nuclear hormone receptor | 255~438 | |
| PF00105 | zf-C4 - Double treble clef zinc finger, C4 type | 12~79 |
3D structures mapped by conservation among orthologs
[ Domain: "Nuclear receptor ligand-binding domain" // Hormone_recep_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL408947 |  |
IC50 | = | 110.0 | nM | 422.48 | CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(=O)Nc3ccc(CC)cc3)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL265938 |  |
IC50 | = | 190.0 | nM | 438.48 | CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(=O)Nc3ccc(OCC)cc3)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL410467 |  |
IC50 | = | 200.0 | nM | 478.42 | CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(=O)Nc3ccc(OC(F)(F)F)cc3)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL262079 |  |
IC50 | = | 200.0 | nM | 424.45 | CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(=O)Nc3ccc(OC)cc3)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL408702 |  |
IC50 | = | 260.0 | nM | 452.46 | CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(=O)NCc3ccc4c(c3)OCO4)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL412079 |  |
IC50 | = | 340.0 | nM | 408.45 | CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(=O)Nc3ccc(C)cc3)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL411889 |  |
IC50 | = | 360.0 | nM | 450.54 | CCCCc1ccc(NC(=O)Cn2ccc3c(OC(C)C(=O)OCC)cccc3c2=O)cc1 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL412080 |  |
IC50 | = | 360.0 | nM | 422.48 | CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(=O)NCCc3ccccc3)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL260592 |  |
IC50 | = | 530.0 | nM | 439.42 | CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(=O)Nc3ccc([N+](=O)[O-])cc3)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL260420 |  |
IC50 | = | 590.0 | nM | 466.49 | CCOC(=O)C(C)(C)Oc1cccc2c(=O)n(CC(=O)Nc3ccc4c(c3)OCCO4)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL261115 |  |
IC50 | = | 680.0 | nM | 426.44 | CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(=O)NCc3ccc(F)cc3)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL259067 |  |
IC50 | = | 760.0 | nM | 452.46 | CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(=O)Nc3ccc4c(c3)OCCO4)ccc12 | Homo sapiens | CHEMBL924745 | single protein format |
| CHEMBL1552719 |  |
IC50 | = | 790.0 | nM | 456.53 | COc1ccc(-n2c(SCc3nc(-c4ccc(C)cc4)no3)nnc2-c2ccncc2)cc1 | Homo sapiens | CHEMBL5227360 | cell-based format |