Q13003 | GRIK3_HUMAN | Glutamate receptor ionotropic, kainate 3 (GRIK3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00060 | Lig_chan - Ligand-gated ion channel | 563~832 | |
| PF01094 | ANF_receptor - Receptor family ligand binding region | 56~399 | |
| PF10613 | Lig_chan-Glu_bd - Ligated ion channel L-glutamate- and glycine-binding site | 435~547 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL275040 |  |
Ki | = | 10.0 | nM | 213.23 | C=C(C)[C@H]1CN[C@H](C(=O)O)[C@H]1CC(=O)O | Homo sapiens | CHEMBL701553 | single protein format |
| CHEMBL59284 |  |
Ki | = | 42.0 | nM | 293.32 | COc1ccccc1/C=C/C[C@H](C[C@H](N)C(=O)O)C(=O)O | Homo sapiens | CHEMBL701555 | cell-based format |
| CHEMBL13076 |  |
Ki | = | 46.0 | nM | 546.42 | O=C(O)Cn1c(=O)c(=O)[nH]c2cc(C(F)(F)F)c(-n3ccc(CNC(=O)Nc4ccc([N+](=O)[O-])cc4)c3)cc21 | Homo sapiens | CHEMBL683952 | cell-based format |
| CHEMBL5193862 |  |
Ki | = | 142.0 | nM | 383.26 | O=C(Nn1c(=O)c(=O)[nH]c2cc(C(F)(F)F)c(F)cc21)c1ccccc1O | Homo sapiens | CHEMBL5114210 | single protein format |
| CHEMBL58590 |  |
Ki | = | 423.0 | nM | 297.74 | N[C@@H](C[C@@H](C/C=C/c1ccc(Cl)cc1)C(=O)O)C(=O)O | Homo sapiens | CHEMBL701553 | single protein format |
| CHEMBL299180 |  |
Ki | = | 518.0 | nM | 201.22 | CC(C)/C=C(\C[C@H](N)C(=O)O)C(=O)O | Homo sapiens | CHEMBL701554 | cell-based format |
| CHEMBL416685 |  |
Ki | = | 530.0 | nM | 503.52 | O=C(O)Cn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccc(CN4CCC(c5ccccc5)CC4)c3)cc21 | Homo sapiens | CHEMBL683952 | cell-based format |
| CHEMBL301536 |  |
Ki | = | 617.0 | nM | 313.35 | N[C@@H](C[C@@H](C/C=C/c1ccc2ccccc2c1)C(=O)O)C(=O)O | Homo sapiens | CHEMBL701553 | single protein format |
| CHEMBL63861 |  |
Ki | = | 680.0 | nM | 518.53 | O=C(O)Cn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccc(CN4CCN(Cc5ccccc5)CC4)c3)cc21 | Homo sapiens | CHEMBL683952 | cell-based format |
| CHEMBL575060 |  |
Ki | = | 789.0 | nM | 147.13 | N[C@@H](CCC(=O)O)C(=O)O | Homo sapiens | CHEMBL701553 | single protein format |