Q12923 | PTN13_HUMAN | Tyrosine-protein phosphatase non-receptor type 13 (PTPN13)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
Accession | Domain | Range | Color |
---|---|---|---|
PF00102 | Y_phosphatase | 2237–2465 | |
PF00373 | FERM_M | 666–781 | |
PF00595 | PDZ | 1094–1175 | |
PF00595 | PDZ | 1369–1449 | |
PF00595 | PDZ | 1502–1583 | |
PF00595 | PDZ | 1789–1865 | |
PF00595 | PDZ | 1889–1954 | |
PF09379 | FERM_N | 576–637 | |
PF09380 | FERM_C | 788–875 | |
PF16599 | PTN13_u3 | 1177–1367 |
3D structures mapped by conservation among orthologs
[ Domain: "PDZ domain" // PDZ ]
[ Domain: "(Phosphotyrosine protein) phosphatases II" // Y_phosphatase ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
---|---|---|---|---|---|---|---|---|---|---|
CHEMBL2396718 | IC50 | = | 390.0 | nM | 503.94 | CCCNC(=O)COc1ccc(-c2oc3cc(O)c(C(=O)O)cc3c2C#Cc2cccc(Cl)c2)cc1 | Homo sapiens | CHEMBL2401196 | single protein format | |
CHEMBL50878 | IC50 | = | 600.0 | nM | 345.33 | O=C(Nc1ccc2c(c1)C(=O)C(=O)c1ccccc1-2)c1ccccc1F | Homo sapiens | CHEMBL680036 | single protein format |