Q12923 | PTN13_HUMAN | Tyrosine-protein phosphatase non-receptor type 13 (PTPN13)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00102 | Y_phosphatase - Protein-tyrosine phosphatase | 2237~2465 | |
| PF00373 | FERM_M - FERM central domain | 666~781 | |
| PF00595 | PDZ - PDZ domain | 1094~1175 | |
| PF00595 | PDZ - PDZ domain | 1369~1449 | |
| PF00595 | PDZ - PDZ domain | 1502~1583 | |
| PF00595 | PDZ - PDZ domain | 1789~1865 | |
| PF00595 | PDZ - PDZ domain | 1889~1954 | |
| PF09379 | FERM_N - FERM N-terminal domain | 576~637 | |
| PF09380 | FERM_C - FERM C-terminal PH-like domain | 788~875 | |
| PF16599 | PTN13_u3 - Unstructured linker region on PTN13 protein between PDZ | 1177~1367 |
3D structures mapped by conservation among orthologs
[ Domain: "PDZ domain" // PDZ ]
[ Domain: "(Phosphotyrosine protein) phosphatases II" // Y_phosphatase ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2396718 |  |
IC50 | = | 390.0 | nM | 503.94 | CCCNC(=O)COc1ccc(-c2oc3cc(O)c(C(=O)O)cc3c2C#Cc2cccc(Cl)c2)cc1 | Homo sapiens | CHEMBL2401196 | single protein format |
| CHEMBL50878 |  |
IC50 | = | 600.0 | nM | 345.33 | O=C(Nc1ccc2c(c1)C(=O)C(=O)c1ccccc1-2)c1ccccc1F | Homo sapiens | CHEMBL680036 | single protein format |