Q12888 | TP53B_HUMAN | TP53-binding protein 1 (TP53BP1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF09038 | 53-BP1_Tudor | 1483–1604 | |
| PF18428 | BRCT_3 | 1867–1969 |
3D structures mapped by conservation among orthologs
[ Domain: "SH3" // 53-BP1_Tudor_C ]
[ Domain: "SH3" // 53-BP1_Tudor_N ]
[ Domain: "BRCT domain" // PTCB-BRCT ]
[ Domain: "BRCT domain" // KOG3548_3rd ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5439383 |  |
IC50 | = | 460.0 | nM | 538.65 | CN1CCN(c2ccnc(C(=O)N3CCC[C@H](C(=O)Nc4cccc(-c5ccc6c(c5)C(=O)NC6)c4)C3)c2)CC1 | Homo sapiens | CHEMBL5373000 | cell-based format |
| CHEMBL5403027 |  |
IC50 | = | 470.0 | nM | 526.64 | CN1CCN(c2ccnc(C(=O)N3CCC[C@H](C(=O)Nc4cccc(-c5ccc(C(N)=O)cc5)c4)C3)c2)CC1 | Homo sapiens | CHEMBL5373000 | cell-based format |