Q09013 | DMPK_HUMAN | Myotonin-protein kinase (DMPK)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 71~339 | |
| PF08826 | DMPK_coil - DMPK coiled coil domain like | 470~530 |
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3218297 |  |
IC50 | = | 34.06 | nM | 422.49 | CS(=O)(=O)O.O=C(NCc1cccc(O)c1)Nc1nc(-c2ccncc2)cs1 | Homo sapiens | CHEMBL3224482 | single protein format |
| CHEMBL4439133 |  |
IC50 | = | 64.6 | nM | 388.32 | Cc1n[nH]cc1-c1cc2nc([C@@H]3CCCCN3)[nH]c(=O)c2s1.Cl.Cl | Homo sapiens | CHEMBL4325337 | assay format |
| CHEMBL388978 |  |
IC50 | = | 105.0 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328387 | single protein format |
| CHEMBL10 |  |
IC50 | < | 1000.0 | nM | 377.44 | C[S+]([O-])c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 | Homo sapiens | CHEMBL4602943 | single protein format |