Q07812 | BAX_HUMAN | Apoptosis regulator BAX (BAX)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00452 | Bcl-2 - Apoptosis regulator proteins, Bcl-2 family | 63~158 |
3D structures mapped by conservation among orthologs
[ Domain: "Bcl-2 inhibitors of programmed cell death" // Bcl-2 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4579601 |  |
IC50 | = | 43.0 | nM | 315.33 | O=[N+]([O-])c1ccc2c(c1)C(=Cc1ccccc1O)c1ccccc1-2 | Homo sapiens | CHEMBL4366071 | single protein format |
| CHEMBL4790235 |  |
IC50 | = | 250.0 | nM | 430.52 | O=C1/C(=N\Nc2nccs2)C(c2ccccc2)=NN1c1nc(-c2ccccc2)cs1 | Homo sapiens | CHEMBL4671937 | single protein format |
| CHEMBL5282360 |  |
IC50 | = | 250.0 | nM | 432.53 | O=C1/C(=N/Nc2nccs2)C(c2ccccc2)=NN1C1=NC(c2ccccc2)CS1 | Homo sapiens | CHEMBL5241703 | assay format |
| CHEMBL4868313 |  |
Ki | = | 43.0 | nM | 315.33 | O=[N+]([O-])c1ccc2c(c1)/C(=C/c1ccccc1O)c1ccccc1-2 | Homo sapiens | CHEMBL4821557 | single protein format |
| CHEMBL3417402 |  |
Ki | = | 800.0 | nM | 457.53 | CCOc1ccccc1N/N=C1\C(=O)N(c2cc(O)cc(-c3ccc(N(C)C)cc3)c2)N=C1C | Homo sapiens | CHEMBL3417877 | assay format |
| CHEMBL3417409 |  |
Ki | = | 1000.0 | nM | 463.54 | CC1=NN(c2cc(O)cc(-c3ccc(N(C)C)cc3)c2)C(=O)/C1=N\Nc1ccc2ccccc2c1 | Homo sapiens | CHEMBL3417877 | assay format |