3D structures mapped by conservation among orthologs

[ Domain: "Ribosomal protein S2/SIS domain" // SIS_3 ]

 PyMOL session

[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

 IC50 CSV    Ki CSV

Only the first 20 rows are shown.

molecule_chembl_id	structure	assay_type	relation	value	unit	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL1911372		IC50	=	150.0	nM	225.04	N[C@@H](CNC(=O)CBr)C(=O)O	Homo sapiens	CHEMBL1912256	single protein format
CHEMBL1911373		IC50	=	400.0	nM	216.19	COC(=O)/C=C/C(=O)NC[C@H](N)C(=O)O	Homo sapiens	CHEMBL1912256	single protein format
CHEMBL1911368		Ki	=	300.0	nM	512.51	COc1cc2c(CNS(=O)(=O)C(F)(F)F)cnc(C(=O)c3cccc(OC(C)C)c3)c2cc1OC	Homo sapiens	CHEMBL1912253	single protein format