Q05209 | PTN12_HUMAN | Tyrosine-protein phosphatase non-receptor type 12 (PTPN12)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00102 | Y_phosphatase - Protein-tyrosine phosphatase | 58~291 |
3D structures mapped by conservation among orthologs
[ Domain: "SH3" // SH3_1 ]
[ Domain: "(Phosphotyrosine protein) phosphatases II" // Y_phosphatase ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4750435 |  |
IC50 | = | 130.0 | nM | 488.5 | COc1ccc(-n2cc(-c3ccc4ccc(=O)oc4c3)c3cc(-c4ccc(C(=O)O)cc4)cnc32)cc1 | Homo sapiens | CHEMBL4712048 | single protein format |
| CHEMBL2396718 |  |
IC50 | = | 800.0 | nM | 503.94 | CCCNC(=O)COc1ccc(-c2oc3cc(O)c(C(=O)O)cc3c2C#Cc2cccc(Cl)c2)cc1 | Homo sapiens | CHEMBL2401195 | single protein format |