Q05193 | DYN1_HUMAN | Dynamin-1 (DNM1)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00169 | PH | 520–621 | |
| PF00350 | Dynamin_N | 34–207 | |
| PF01031 | Dynamin_M | 215–501 | |
| PF02212 | GED | 656–744 |
3D structures mapped by conservation among orthologs
[ Domain: "PH domain-like" // PH ]
[ Domain: "Middle and GTPase effector domains in dynamin-related proteins" // Dynamin_M ]
[ Domain: "P-loop containing nucleoside triphosphate hydrolases" // Dynamin_N ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5397838 |  |
IC50 | = | 1000.0 | nM | 344.46 | Cc1ccc(CNCC(O)Cn2c3ccccc3c3ccccc32)cc1 | Homo sapiens | CHEMBL5356087 | single protein format |
| CHEMBL5400843 |  |
IC50 | = | 1000.0 | nM | 364.88 | OC(CNCc1ccc(Cl)cc1)Cn1c2ccccc2c2ccccc21 | Homo sapiens | CHEMBL5356087 | single protein format |