Q02790 | FKBP4_HUMAN | Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4)

Pfam Domain Table

AccessionDomainRangeColor
PF00254FKBP_C - FKBP-type peptidyl-prolyl cis-trans isomerase44~134
PF00254FKBP_C - FKBP-type peptidyl-prolyl cis-trans isomerase162~250
PF00515TPR_1 - Tetratricopeptide repeat321~352
PF07719TPR_2 - Tetratricopeptide repeat354~386

3D structures mapped by conservation among orthologs

[ Domain: "ARM repeat" // TPR_11_8 ]

 PyMOL session

[ Domain: "FKBP-like" // FKBP_C ]

 PyMOL session


[ Alpha Fold Model ] (go)



Known binders annotated in ChEMBL

 Ki CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL4090599 Ki = 18.9 nM 498.43 COC[C@H]1CN(Cc2ccccn2)C(=O)[C@@H]2CCC[C@H]1N2S(=O)(=O)c1cc(Cl)cc(Cl)c1 Homo sapiens CHEMBL4048819 single protein format
CHEMBL321022 Ki = 20.0 nM 583.68 CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccc(OC)c(OC)c1)c1cccc(OCC(=O)O)c1 Homo sapiens CHEMBL5253379 single protein format
CHEMBL6367 Ki = 936.0 nM 360.45 CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(=O)OCCCc1cccnc1 Homo sapiens CHEMBL5253379 single protein format