Q01650 | LAT1_HUMAN | Large neutral amino acids transporter small subunit 1 (SLC7A5)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF13520 | AA_permease_2 - Amino acid permease | 51~467 |
3D structures mapped by conservation among orthologs
[ Domain: "Sodium:neurotransmitter symporter family (SNF)-like" // AA_permease_2_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4538666 |  |
IC50 | = | 790.0 | nM | 472.33 | Nc1cc(COc2c(Cl)cc(C[C@H](N)C(=O)O)cc2Cl)c2oc(-c3ccccc3)nc2c1 | Homo sapiens | CHEMBL4425979 | cell-based format |
| CHEMBL4526588 |  |
IC50 | = | 980.0 | nM | 313.71 | FC(F)(F)Oc1ccc(/N=c2\ssnc2Cl)nc1 | Homo sapiens | CHEMBL4407759 | single protein format |