Q01469 | FABP5_HUMAN | Fatty acid-binding protein 5 (FABP5)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00061 | Lipocalin - Lipocalin / cytosolic fatty-acid binding protein family | 9~133 |
3D structures mapped by conservation among orthologs
[ Domain: "Lipocalins" // Lipocalin_7 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3923099 |  |
IC50 | = | 16.0 | nM | 455.61 | Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c1-c1nc(C2CC2)ns1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL5278217 |  |
IC50 | = | 20.0 | nM | 459.64 | CCCCCC1CCc2nc(C3(COC)CCCC3)c(-c3nnn[nH]3)c(-c3ccccc3)c2C1 | Homo sapiens | CHEMBL5262838 | single protein format |
| CHEMBL3914116 |  |
IC50 | = | 22.0 | nM | 415.54 | Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)ns1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3920801 |  |
IC50 | = | 22.0 | nM | 429.57 | Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C3CC3)ns2)c1C | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL5287082 |  |
IC50 | = | 30.0 | nM | 404.52 | Cc1cc(-c2c3c(nc(C4(CO)CCCC4)c2-c2nnn[nH]2)CCCCC3)ccn1 | Homo sapiens | CHEMBL5262838 | single protein format |
| CHEMBL3896829 |  |
IC50 | = | 30.0 | nM | 427.4 | Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C(F)(F)F)no2)c1C1CC1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3918729 |  |
IC50 | = | 30.0 | nM | 399.47 | Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3896498 |  |
IC50 | = | 30.0 | nM | 399.47 | Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C1CC1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3957282 |  |
IC50 | = | 30.0 | nM | 389.5 | Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc(C3CC3)c2C)n1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3919426 |  |
IC50 | = | 30.0 | nM | 373.43 | Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)no2)c1C | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3986878 |  |
IC50 | = | 31.0 | nM | 377.49 | Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCCC3)sc(C)c2C)n1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3938613 |  |
IC50 | = | 31.0 | nM | 429.57 | Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)C4CCC3CC4)sc(C3CC3)c2C)n1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3915309 |  |
IC50 | = | 38.0 | nM | 389.5 | Cc1sc(NC(=O)C2=C(C(=O)O)CCC2)c(-c2nc(C3CC3)ns2)c1C | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3903803 |  |
IC50 | = | 38.8 | nM | 385.45 | O=C(O)C1=C(C(=O)Nc2scc(C3CC3)c2-c2nc(C3CC3)no2)CCC1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3929717 |  |
IC50 | = | 39.0 | nM | 403.53 | Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCCC3)sc(C3CC3)c2C)n1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3967672 |  |
IC50 | = | 40.0 | nM | 439.54 | Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C3CC3)no2)c1C1CC1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL5281007 |  |
IC50 | = | 40.0 | nM | 388.52 | Cc1cc(-c2c3c(nc(C4(C)CCCC4)c2-c2nnn[nH]2)CCCCC3)ccn1 | Homo sapiens | CHEMBL5262838 | single protein format |
| CHEMBL3920664 |  |
IC50 | = | 40.0 | nM | 429.57 | Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)CCCC2)c1-c1nc(C2CC2)ns1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3897486 |  |
IC50 | = | 40.9 | nM | 413.38 | O=C(O)C1=C(C(=O)Nc2scc(C(F)(F)F)c2-c2nc(C3CC3)no2)CCC1 | Homo sapiens | CHEMBL3888564 | single protein format |
| CHEMBL3950827 |  |
IC50 | = | 41.0 | nM | 363.46 | Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc(C)c2C)n1 | Homo sapiens | CHEMBL3888564 | single protein format |