Q00266 | METK1_HUMAN | S-adenosylmethionine synthase isoform type-1 (MAT1A)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00438 | S-AdoMet_synt_N | 18–115 | |
| PF02772 | S-AdoMet_synt_M | 130–250 | |
| PF02773 | S-AdoMet_synt_C | 252–388 |
3D structures mapped by conservation among orthologs
[ Domain: "S-adenosylmethionine synthetase" // S-AdoMet_synt_C ]
[ Domain: "S-adenosylmethionine synthetase" // S-AdoMet_synt_M ]
[ Domain: "S-adenosylmethionine synthetase" // S-AdoMet_synt_N ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5427280 |  |
IC50 | = | 813.0 | nM | 343.79 | O=c1nc(N2CC[C@@H](F)C2)c2ccc(Cl)cc2n1-c1ccccc1 | Homo sapiens | CHEMBL5366308 | single protein format |