P81172 | HEPC_HUMAN | Hepcidin (HAMP)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF06446 | Hepcidin | 33–84 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5184000 |  |
IC50 | = | 7.3 | nM | 465.56 | COC(=O)N1C[C@@H](C)N(c2ncc3[nH]nc(-c4ccc(N5CCN[C@H](C)C5)nc4)c3n2)[C@@H](C)C1 | Homo sapiens | CHEMBL5125838 | cell-based format |
| CHEMBL5199417 |  |
IC50 | = | 28.0 | nM | 504.64 | C[C@@H]1CN(c2ccc(-c3n[nH]c4cnc(N5[C@H](C)CN(C(=O)N6CCCC6)C[C@@H]5C)nc34)cn2)CCN1 | Homo sapiens | CHEMBL5125838 | cell-based format |
| CHEMBL5181536 |  |
IC50 | = | 34.0 | nM | 464.57 | COC(=O)N1C[C@@H](C)N(c2ncc3[nH]nc(-c4ccc(N5CCN(C)CC5)cc4)c3n2)[C@@H](C)C1 | Homo sapiens | CHEMBL5125838 | cell-based format |
| CHEMBL5186341 |  |
IC50 | = | 58.0 | nM | 465.56 | COC(=O)N1C[C@@H](C)N(c2ncc3[nH]nc(-c4ccc(N5CCN(C)CC5)nc4)c3n2)[C@@H](C)C1 | Homo sapiens | CHEMBL5125838 | cell-based format |