P78540 | ARGI2_HUMAN | Arginase-2, mitochondrial (ARG2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00491 | Arginase - Arginase family | 25~321 |
3D structures mapped by conservation among orthologs
[ Domain: "Arginase/deacetylase" // Arginase ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4764455 |  |
IC50 | = | 0.1 | nM | 338.2 | NCCNS(=O)(=O)N1C[C@H](CCCB(O)O)[C@](N)(C(=O)O)C1 | Homo sapiens | CHEMBL4729733 | single protein format |
| CHEMBL4745275 |  |
IC50 | = | 4.0 | nM | 244.1 | N[C@H]1CCN[C@@](CCCCB(O)O)(C(=O)O)C1 | Homo sapiens | CHEMBL4672977 | assay format |
| CHEMBL1812661 |  |
IC50 | = | 8.5 | nM | 174.99 | N[C@@H](CCCCB(O)O)C(=O)O | Homo sapiens | CHEMBL5241487 | single protein format |
| CHEMBL4749355 |  |
IC50 | = | 10.0 | nM | 244.1 | CN[C@H]1CN[C@@](CCCCB(O)O)(C(=O)O)C1 | Homo sapiens | CHEMBL4729736 | single protein format |
| CHEMBL4757930 |  |
IC50 | = | 15.0 | nM | 357.26 | CC(C)C[C@H](N)C(=O)N[C@H]1CCN[C@@](CCCCB(O)O)(C(=O)O)C1 | Homo sapiens | CHEMBL4672977 | assay format |
| CHEMBL4752307 |  |
IC50 | = | 20.0 | nM | 230.07 | N[C@H]1CN[C@@](CCCCB(O)O)(C(=O)O)C1 | Homo sapiens | CHEMBL4729736 | single protein format |
| CHEMBL4753285 |  |
IC50 | = | 21.0 | nM | 357.26 | CC[C@H](C)[C@H](N)C(=O)N[C@H]1CCN[C@@](CCCCB(O)O)(C(=O)O)C1 | Homo sapiens | CHEMBL4672977 | assay format |
| CHEMBL4752391 |  |
IC50 | = | 21.0 | nM | 329.21 | CC[C@H](N)C(=O)N[C@H]1CCN[C@@](CCCCB(O)O)(C(=O)O)C1 | Homo sapiens | CHEMBL4672977 | assay format |
| CHEMBL2418831 |  |
IC50 | = | 23.0 | nM | 443.18 | NC(CCCCB(O)O)(C(=O)O)C1CC2CCC(C1)N2Cc1ccc(Cl)c(Cl)c1 | Homo sapiens | CHEMBL2423683 | single protein format |
| CHEMBL4750174 |  |
IC50 | = | 24.0 | nM | 357.26 | CC(C)(C)[C@H](N)C(=O)N[C@H]1CCN[C@@](CCCCB(O)O)(C(=O)O)C1 | Homo sapiens | CHEMBL4672977 | assay format |
| CHEMBL4778086 |  |
IC50 | = | 24.0 | nM | 343.23 | CC(C)[C@H](N)C(=O)N[C@H]1CCN[C@@](CCCCB(O)O)(C(=O)O)C1 | Homo sapiens | CHEMBL4672977 | assay format |
| CHEMBL4244287 |  |
IC50 | = | 30.0 | nM | 193.03 | N[C@@H](CSCCB(O)O)C(=O)O | Homo sapiens | CHEMBL5241487 | single protein format |
| CHEMBL2418830 |  |
IC50 | = | 30.0 | nM | 408.74 | NC(CCCCB(O)O)(C(=O)O)C1CC2CCC(C1)N2Cc1ccc(Cl)cc1 | Homo sapiens | CHEMBL2423683 | single protein format |
| CHEMBL2418991 |  |
IC50 | = | 33.0 | nM | 410.27 | NC(CCCCB(O)O)(C(=O)O)C1CC2CCC(C1)N2Cc1ccc(F)c(F)c1 | Homo sapiens | CHEMBL2423683 | single protein format |
| CHEMBL2418829 |  |
IC50 | = | 47.0 | nM | 374.29 | NC(CCCCB(O)O)(C(=O)O)C1CC2CCC(C1)N2Cc1ccccc1 | Homo sapiens | CHEMBL2423683 | single protein format |
| CHEMBL2418998 |  |
IC50 | = | 50.0 | nM | 445.2 | NC(CCCCB(O)O)(C(=O)O)C1CCN(CCCc2ccc(Cl)cc2Cl)CC1 | Homo sapiens | CHEMBL2423683 | single protein format |
| CHEMBL1234777 |  |
IC50 | = | 51.0 | nM | 176.18 | N=C(NO)NCC[C@H](N)C(=O)O | Homo sapiens | CHEMBL5241487 | single protein format |
| CHEMBL2326090 |  |
IC50 | = | 67.0 | nM | 300.21 | CN[C@](CCCCB(O)O)(CCN1CCCCC1)C(=O)O | Homo sapiens | CHEMBL2330668 | assay format |
| CHEMBL2418999 |  |
IC50 | = | 70.0 | nM | 444.3 | NC(CCCCB(O)O)(C(=O)O)C1CCN(CCCc2ccc(C(F)(F)F)cc2)CC1 | Homo sapiens | CHEMBL2423683 | single protein format |
| CHEMBL2418828 |  |
IC50 | = | 85.0 | nM | 284.17 | NC(CCCCB(O)O)(C(=O)O)C1CC2CCC(C1)N2 | Homo sapiens | CHEMBL2423683 | single protein format |