P78417 | GSTO1_HUMAN | Glutathione S-transferase omega-1 (GSTO1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF13409 | GST_N_2 - Glutathione S-transferase, N-terminal domain | 31~95 | |
| PF14497 | GST_C_3 - Glutathione S-transferase, C-terminal domain | 140~218 |
3D structures mapped by conservation among orthologs
[ Domain: "Glutathione S-transferase (GST)-C" // GST_C_3 ]
[ Domain: "Thioredoxin-like" // GST_N ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4593975 |  |
IC50 | = | 0.22 | nM | 341.39 | C=CC(=O)N(Cc1cc(C)no1)c1nc(-c2ccccc2O)cs1 | Homo sapiens | CHEMBL4401249 | single protein format |
| CHEMBL4513682 |  |
IC50 | = | 0.32 | nM | 375.84 | C=CC(=O)N(Cc1cc(C)no1)c1nc(-c2ccc(Cl)cc2O)cs1 | Homo sapiens | CHEMBL4401249 | single protein format |
| CHEMBL4463748 |  |
IC50 | = | 5.6 | nM | 363.83 | Cc1cc(CN(C(=O)CCl)c2nc(-c3ccccc3O)cs2)on1 | Homo sapiens | CHEMBL4401249 | single protein format |
| CHEMBL4443686 |  |
IC50 | = | 25.0 | nM | 393.39 | C=CC(=O)N(Cc1cc(C)no1)c1nc(-c2ccc(C(F)(F)F)cc2)cs1 | Homo sapiens | CHEMBL4401249 | single protein format |
| CHEMBL1502738 |  |
IC50 | = | 28.0 | nM | 367.71 | O=C(CCl)N(CCCNC(=O)C(F)(F)F)c1ccc([N+](=O)[O-])cc1 | Homo sapiens | CHEMBL4199255 | single protein format |
| CHEMBL4529442 |  |
IC50 | = | 30.0 | nM | 343.41 | C=CC(=O)N(CC(=O)NC1COC1)c1nc(-c2ccccc2)cs1 | Homo sapiens | CHEMBL4401249 | single protein format |
| CHEMBL4445050 |  |
IC50 | = | 30.0 | nM | 341.22 | COCCNS(=O)(=O)c1cc(NC(=O)CCl)ccc1Cl | Homo sapiens | CHEMBL4404678 | assay format |
| CHEMBL4210652 |  |
IC50 | = | 31.0 | nM | 311.19 | CN(C)S(=O)(=O)c1cc(NC(=O)CCl)ccc1Cl | Homo sapiens | CHEMBL4199255 | single protein format |
| CHEMBL4215608 |  |
IC50 | = | 35.0 | nM | 403.89 | O=C(NC1CCCCC1)C(c1ccccn1)N(C(=O)CCl)c1cccc(F)c1 | Homo sapiens | CHEMBL4199259 | cell-based format |
| CHEMBL4568270 |  |
IC50 | = | 40.0 | nM | 359.38 | C=CC(=O)N(Cc1cc(C)no1)c1nc(-c2ccc(F)cc2O)cs1 | Homo sapiens | CHEMBL4401249 | single protein format |
| CHEMBL4203414 |  |
IC50 | = | 40.0 | nM | 460.57 | CC(C)CCCC(C)CCOc1ccc2c(ccc3oc(C4(O)C=CC(=O)C=C4)cc(=O)c32)c1 | Homo sapiens | CHEMBL4199258 | single protein format |
| CHEMBL4454963 |  |
IC50 | = | 51.0 | nM | 325.39 | C=CC(=O)N(Cc1cc(C)no1)c1nc(-c2ccccc2)cs1 | Homo sapiens | CHEMBL4401249 | single protein format |
| CHEMBL1486332 |  |
IC50 | = | 54.0 | nM | 403.89 | O=C(NC1CCCCC1)C(c1cccnc1)N(C(=O)CCl)c1ccc(F)cc1 | Homo sapiens | CHEMBL4199255 | single protein format |
| CHEMBL4458115 |  |
IC50 | = | 60.0 | nM | 344.74 | CN(C)S(=O)(=O)c1cc(NC(=O)CCl)ccc1C(F)(F)F | Homo sapiens | CHEMBL4404678 | assay format |
| CHEMBL4454026 |  |
IC50 | = | 70.0 | nM | 325.22 | CC(C)NS(=O)(=O)c1cc(NC(=O)CCl)ccc1Cl | Homo sapiens | CHEMBL4404678 | assay format |
| CHEMBL4443397 |  |
IC50 | = | 80.0 | nM | 369.49 | C=CC(=O)N(CC(=O)NC1CCCCC1)c1nc(-c2ccccc2)cs1 | Homo sapiens | CHEMBL4401249 | single protein format |
| CHEMBL4458365 |  |
IC50 | = | 80.0 | nM | 355.24 | COCCN(C)S(=O)(=O)c1cc(NC(=O)CCl)ccc1Cl | Homo sapiens | CHEMBL4404678 | assay format |
| CHEMBL4437777 |  |
IC50 | = | 110.0 | nM | 355.24 | COCCCNS(=O)(=O)c1cc(NC(=O)CCl)ccc1Cl | Homo sapiens | CHEMBL4404678 | assay format |
| CHEMBL1598561 |  |
IC50 | = | 120.0 | nM | 496.05 | COc1ccc(CN(CCC(c2ccccc2)c2ccc(OC(C)C)cc2)C(=O)CCl)cc1OC | Homo sapiens | CHEMBL4199258 | single protein format |
| CHEMBL4588856 |  |
IC50 | = | 130.0 | nM | 402.64 | CN(C)S(=O)(=O)c1cc(NC(=O)CCl)ccc1I | Homo sapiens | CHEMBL4404678 | assay format |