P78368 | KC1G2_HUMAN | Casein kinase I isoform gamma-2 (CSNK1G2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 47~262 | |
| PF12605 | CK1gamma_C - Casein kinase 1 gamma C terminal | 361~385 |
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2203556 |  |
IC50 | = | 8.0 | nM | 335.37 | COc1cnc(Nc2ccccc2)nc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211471 | single protein format |
| CHEMBL2203554 |  |
IC50 | = | 17.0 | nM | 366.4 | COc1cnc(CCc2ccc(F)cc2)nc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211471 | single protein format |
| CHEMBL2203559 |  |
IC50 | = | 24.0 | nM | 368.37 | COc1cnc(COc2ccc(F)cc2)nc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211471 | single protein format |
| CHEMBL2203555 |  |
IC50 | = | 33.0 | nM | 349.39 | COc1cnc(NCc2ccccc2)nc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211471 | single protein format |
| CHEMBL2203565 |  |
IC50 | = | 44.0 | nM | 399.4 | COc1cnc(COc2cc(F)c(F)cc2C)cc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211457 | single protein format |
| CHEMBL2203553 |  |
IC50 | = | 50.0 | nM | 364.38 | COc1cnc(/C=C/c2ccc(F)cc2)nc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211471 | single protein format |
| CHEMBL2203557 |  |
IC50 | = | 80.0 | nM | 368.37 | COc1cnc(OCc2ccc(F)cc2)nc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211471 | single protein format |
| CHEMBL2203563 |  |
IC50 | = | 254.0 | nM | 385.37 | COc1cnc(COc2ccc(F)c(F)c2)cc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211457 | single protein format |
| CHEMBL2203552 |  |
IC50 | = | 348.0 | nM | 371.4 | COc1cnc(-c2cnc3ccccc3c2)nc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211467 | cell-based format |
| CHEMBL2203562 |  |
IC50 | = | 394.0 | nM | 385.37 | COc1cnc(COc2ccc(F)cc2F)cc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211457 | single protein format |
| CHEMBL2203564 |  |
IC50 | = | 537.0 | nM | 381.41 | COc1cnc(COc2ccc(F)cc2C)cc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211457 | single protein format |
| CHEMBL2203561 |  |
IC50 | = | 584.0 | nM | 367.38 | COc1cnc(COc2ccc(F)cc2)cc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211457 | single protein format |
| CHEMBL2071614 |  |
IC50 | = | 700.0 | nM | 292.34 | CC(C)(O)c1ccc(Nc2nc3ccc(C#N)cc3[nH]2)cc1 | Homo sapiens | CHEMBL2072010 | cell-based format |
| CHEMBL4081711 |  |
IC50 | = | 710.0 | nM | 361.37 | CC[C@@H]1[C@H](F)C(=O)N[C@@H]1COc1nccc2cc(C(N)=O)c(OC)cc12 | Homo sapiens | CHEMBL5209670 | cell-based format |
| CHEMBL2203560 |  |
IC50 | = | 840.0 | nM | 365.41 | COc1cnc(CCc2ccc(F)cc2)cc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211467 | cell-based format |
| CHEMBL2203558 |  |
IC50 | = | 853.0 | nM | 336.35 | COc1cnc(Oc2ccccc2)nc1-c1cc2c([nH]1)CCNC2=O | Homo sapiens | CHEMBL2211471 | single protein format |