P67870 | CSK2B_HUMAN | Casein kinase II subunit beta (CSNK2B)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01214 | CK_II_beta - Casein kinase II regulatory subunit | 8~191 |
3D structures mapped by conservation among orthologs
[ Domain: "Casein kinase II beta subunit" // CK_II_beta ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3919649 |  |
IC50 | = | 48.7 | nM | 458.48 | O=C1NC(=O)/C(=C/c2cnn3c(NC4CC4)cc(-c4cccc(OCC5=NCCN5)c4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3914148 |  |
IC50 | = | 48.7 | nM | 361.37 | O=C1NC(=O)/C(=C/c2cnn3c(NC4CC4)cc(-c4ccncc4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3922569 |  |
IC50 | = | 75.4 | nM | 385.39 | N#Cc1cccc(-c2cc(NC3CC3)n3ncc(/C=C4\NC(=O)NC4=O)c3n2)c1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3933287 |  |
IC50 | = | 75.4 | nM | 379.36 | O=C1NC(=O)/C(=C/c2cnn3c(NC4CC4)cc(-c4ccnc(F)c4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3928114 |  |
IC50 | = | 197.8 | nM | 406.47 | NCc1cccc(-c2cc(NC3CC3)n3ncc(/C=C4\SC(=O)NC4=O)c3n2)c1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3981518 |  |
IC50 | = | 209.0 | nM | 477.93 | O=C1NC(=O)/C(=C/c2cnn3c([S+]([O-])Cc4ccccc4)cc(-c4cccc(Cl)c4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3954706 |  |
IC50 | = | 217.6 | nM | 396.41 | O=C1NC(=O)/C(=C/c2cnn3c(NC4CC4)cc(-c4ccnc(F)c4)nc23)S1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3976484 |  |
IC50 | = | 253.2 | nM | 396.46 | N[C@H]1CC[C@H](Nc2cc(NC3CC3)n3ncc(/C=C4\NC(=O)NC4=O)c3n2)CC1 | Homo sapiens | CHEMBL3887160 | single protein format |
| CHEMBL3978501 |  |
IC50 | = | 256.2 | nM | 430.47 | O=C1NC(=O)/C(=C/c2cnn3c(NC4CC4)cc(-c4cccc(OCC5CC5)c4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3910845 |  |
IC50 | = | 256.2 | nM | 404.43 | CN(C)c1ccc(-c2cc(NC3CC3)n3ncc(/C=C4\NC(=O)NC4=O)c3n2)cn1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3893330 |  |
IC50 | = | 284.1 | nM | 398.43 | O=C1NC(=O)/C(=C/c2cnn3c(NCC4CC4)cc(NN4CCOCC4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3927192 |  |
IC50 | = | 291.3 | nM | 461.93 | O=C1NC(=O)/C(=C/c2cnn3c(SCc4ccccc4)cc(-c4cccc(Cl)c4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3954928 |  |
IC50 | = | 296.8 | nM | 492.95 | O=C1NC(=O)/C(=C/c2cnn3c([S+]([O-])Cc4ccccc4)cc(Nc4cccc(Cl)c4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3955320 |  |
IC50 | = | 313.9 | nM | 472.43 | C[C@H](Nc1nc(NC2CC2)n2ncc(/C=C3\NC(=O)NC3=O)c2n1)c1ccc(C(F)(F)F)cc1 | Homo sapiens | CHEMBL3887160 | single protein format |
| CHEMBL3917668 |  |
IC50 | = | 316.5 | nM | 427.85 | CC(O)CNc1cc(Nc2cccc(Cl)c2)nc2c(/C=C3\NC(=O)NC3=O)cnn12 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3947068 |  |
IC50 | = | 342.6 | nM | 437.89 | O=C1NC(=O)/C(=C/c2cnn3c(NC4CCCC4)cc(Nc4cccc(Cl)c4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3977510 |  |
IC50 | = | 359.0 | nM | 403.39 | O=C1NC(=O)/C(=C/c2cnn3c(NC4CC4)cc(N4CCC(F)(F)CC4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3940234 |  |
IC50 | = | 421.1 | nM | 460.89 | O=C1NC(=O)/C(=C/c2cnn3c(NCc4ccccn4)cc(Nc4cccc(Cl)c4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3976346 |  |
IC50 | = | 469.0 | nM | 441.88 | CCOCCNc1cc(Nc2cccc(Cl)c2)nc2c(/C=C3\NC(=O)NC3=O)cnn12 | Homo sapiens | CHEMBL3888221 | single protein format |
| CHEMBL3889467 |  |
IC50 | = | 474.7 | nM | 413.83 | O=C1NC(=O)/C(=C/c2cnn3c(NCCO)cc(Nc4cccc(Cl)c4)nc23)N1 | Homo sapiens | CHEMBL3888221 | single protein format |