P61812 | TGFB2_HUMAN | Transforming growth factor beta-2 proprotein (TGFB2)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00019 | TGF_beta | 316–413 | |
| PF00688 | TGFb_propeptide | 22–227 |
3D structures mapped by conservation among orthologs
[ Domain: "Cystine-knot cytokines" // TGF_beta ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5288544 |  |
IC50 | = | 0.34 | nM | 378.37 | CC(=O)Nc1cc(Nc2nc(-c3ccc(F)c(C)n3)nc3[nH]cnc23)ccn1 | Homo sapiens | CHEMBL5264168 | single protein format |
| CHEMBL3704651 |  |
IC50 | = | 4.33 | nM | 320.42 | CCc1cnn(-c2cccc(C)n2)c1-c1cc2cnccc2s1 | Homo sapiens | CHEMBL5264168 | single protein format |
| CHEMBL2364611 |  |
IC50 | = | 56.0 | nM | 369.43 | Cc1cccc(-c2nn3c(c2-c2ccnc4ccc(C(N)=O)cc24)CCC3)n1 | Homo sapiens | CHEMBL5264168 | single protein format |
| CHEMBL5279930 |  |
IC50 | = | 970.0 | nM | 401.47 | O=c1[nH]cc(-c2cccc(CO)c2)cc1-c1nc2cc(N3CCNCC3)ccc2[nH]1 | Homo sapiens | CHEMBL5264168 | single protein format |