P56545 | CTBP2_HUMAN | C-terminal-binding protein 2 (CTBP2)
Pfam Domain Table
Accession | Domain | Range | Color |
---|---|---|---|
PF00389 | 2-Hacid_dh - D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | 44~140 | |
PF00389 | 2-Hacid_dh - D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | 324~358 | |
PF02826 | 2-Hacid_dh_C - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain | 141~323 |
3D structures mapped by conservation among orthologs
[ Domain: "NAD(P)-binding Rossmann-fold domains" // 2-Hacid_dh_C ]
[ Domain: "Formate/glycerate dehydrogenase catalytic domain-like" // 2-Hacid_dh ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
---|---|---|---|---|---|---|---|---|---|---|
CHEMBL3799940 | IC50 | = | 170.0 | nM | 213.62 | O=C(O)/C(Cc1cccc(Cl)c1)=N\O | Homo sapiens | CHEMBL3804623 | cell-based format | |
CHEMBL3798669 | IC50 | = | 180.0 | nM | 213.62 | O=C(O)/C(Cc1ccc(Cl)cc1)=N\O | Homo sapiens | CHEMBL3804623 | cell-based format | |
CHEMBL3797778 | IC50 | = | 240.0 | nM | 179.17 | O=C(O)/C(Cc1ccccc1)=N\O | Homo sapiens | CHEMBL3804623 | cell-based format | |
CHEMBL3800609 | IC50 | = | 300.0 | nM | 197.16 | O=C(O)/C(Cc1ccc(F)cc1)=N\O | Homo sapiens | CHEMBL3804623 | cell-based format | |
CHEMBL3800006 | IC50 | = | 320.0 | nM | 193.2 | Cc1ccc(C/C(=N/O)C(=O)O)cc1 | Homo sapiens | CHEMBL3804623 | cell-based format | |
CHEMBL3800187 | IC50 | = | 480.0 | nM | 193.2 | Cc1cccc(C/C(=N/O)C(=O)O)c1 | Homo sapiens | CHEMBL3804623 | cell-based format | |
CHEMBL3799689 | IC50 | = | 720.0 | nM | 195.17 | O=C(O)/C(Cc1cccc(O)c1)=N\O | Homo sapiens | CHEMBL3804623 | cell-based format | |
CHEMBL3799251 | IC50 | = | 880.0 | nM | 209.2 | COc1cccc(C/C(=N/O)C(=O)O)c1 | Homo sapiens | CHEMBL3804623 | cell-based format | |
CHEMBL3797935 | IC50 | = | 900.0 | nM | 204.19 | N#Cc1ccc(C/C(=N/O)C(=O)O)cc1 | Homo sapiens | CHEMBL3804623 | cell-based format |