P55786 | PSA_HUMAN | Puromycin-sensitive aminopeptidase (NPEPPS)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01433 | Peptidase_M1 - Peptidase family M1 domain | 280~497 | |
| PF11838 | ERAP1_C - ERAP1-like C-terminal domain | 578~891 | |
| PF17900 | Peptidase_M1_N - Peptidase M1 N-terminal domain | 60~245 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3244800 |  |
IC50 | = | 7.4 | nM | 563.68 | CN(C)c1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@@H](N)CSC(c2ccccc2)c2ccccc2)[C@H]1O | Homo sapiens | CHEMBL4132608 | assay format |
| CHEMBL2103847 |  |
IC50 | = | 260.0 | nM | 406.48 | CC(C)C[C@@H](C(=O)N[C@H](C(=O)OC1CCCC1)c1ccccc1)[C@H](O)C(=O)NO | Homo sapiens | CHEMBL4132608 | assay format |
| CHEMBL3244799 |  |
IC50 | = | 940.0 | nM | 487.59 | CN(C)c1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@@H](N)CSCc2ccccc2)[C@H]1O | Homo sapiens | CHEMBL4132608 | assay format |