P55211 | CASP9_HUMAN | Caspase-9 (CASP9)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00619 | CARD | 6–90 | |
| PF00656 | Peptidase_C14 | 161–412 |
3D structures mapped by conservation among orthologs
[ Domain: "DEATH domain" // CARD ]
[ Domain: "Caspase-like" // Peptidase_C14 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL23226 |  |
IC50 | = | 5.0 | nM | 382.39 | CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF | Homo sapiens | CHEMBL659720 | single protein format |
| CHEMBL237310 |  |
IC50 | = | 6.0 | nM | 487.48 | CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1C(=O)NC(C(=O)O)C(=O)CF | Homo sapiens | CHEMBL899140 | single protein format |
| CHEMBL185356 |  |
IC50 | = | 9.0 | nM | 451.28 | CC(C)[C@H](NC(=O)OCc1ccc(Cl)cc1Cl)C(=O)NC(CC(=O)O)C(=O)CF | Homo sapiens | CHEMBL827050 | single protein format |
| CHEMBL180263 |  |
IC50 | = | 30.0 | nM | 368.36 | CC(C)[C@H](OC(=O)Nc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF | Homo sapiens | CHEMBL827040 | single protein format |
| CHEMBL90224 |  |
IC50 | = | 160.0 | nM | 413.47 | CC(C)C[C@H](NC(=O)CNc1cccc2ccccc12)C(=O)N[C@H](C=O)CC(=O)O | Homo sapiens | CHEMBL659719 | single protein format |
| CHEMBL90307 |  |
IC50 | = | 230.0 | nM | 427.46 | CC(C)C[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@H](C=O)CC(=O)O | Homo sapiens | CHEMBL659719 | single protein format |