P54707 | AT12A_HUMAN | Potassium-transporting ATPase alpha chain 2 (ATP12A)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00122 | E1-E2_ATPase - E1-E2 ATPase | 178~369 | |
| PF00689 | Cation_ATPase_C - Cation transporting ATPase, C-terminus | 814~1024 | |
| PF00690 | Cation_ATPase_N - Cation transporter/ATPase, N-terminus | 59~126 | |
| PF00702 | Hydrolase - haloacid dehalogenase-like hydrolase | 603~744 | |
| PF13246 | Cation_ATPase - Cation transport ATPase (P-type) | 441~536 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2068911 |  |
IC50 | = | 30.0 | nM | 433.63 | CN(C)CCOC(=O)/C=C/[C@H]1CC[C@]2(O)[C@@H]3CC[C@@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | Homo sapiens | CHEMBL751505 | single protein format |
| CHEMBL2068890 |  |
IC50 | = | 60.0 | nM | 346.51 | C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](/C=C/C=O)CC[C@]12O | Homo sapiens | CHEMBL751505 | single protein format |
| CHEMBL1453 |  |
IC50 | = | 80.0 | nM | 374.52 | C[C@]12CC[C@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C3=CC(=O)OC3)CC[C@]12O | Homo sapiens | CHEMBL751505 | single protein format |
| CHEMBL323301 |  |
IC50 | = | 100.0 | nM | 405.58 | C[C@H]1/C(=C/C(=O)OCCN(C)C)CCC2C1C(=O)C[C@H]1C(C)(C)[C@@H](O)CC[C@]21C | Homo sapiens | CHEMBL751505 | single protein format |
| CHEMBL104027 |  |
IC50 | = | 120.0 | nM | 433.63 | CC[C@@H](/C=C/C(=O)OCCN(C)C)[C@]1(C)CCC2C(CC[C@@H]3C[C@@H](O)CC[C@]23C)C1=O | Homo sapiens | CHEMBL751505 | single protein format |
| CHEMBL318786 |  |
IC50 | = | 130.0 | nM | 360.54 | CC[C@H](C1=CC(=O)OC1)[C@@]1(C)CCC2C(CC[C@@H]3C[C@@H](O)CC[C@]23C)C1 | Homo sapiens | CHEMBL751505 | single protein format |
| CHEMBL2093999 |  |
IC50 | = | 200.0 | nM | 360.5 | C[C@]12CCC(=NOCCN)C[C@@H]1C(=O)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 | Homo sapiens | CHEMBL751507 | single protein format |
| CHEMBL319670 |  |
IC50 | = | 200.0 | nM | 374.52 | CC[C@H](C1=CC(=O)OC1)[C@@]1(C)CCC2C(CC[C@@H]3C[C@@H](O)CC[C@]23C)C1=O | Homo sapiens | CHEMBL751505 | single protein format |
| CHEMBL321090 |  |
IC50 | = | 250.0 | nM | 433.63 | CC[C@H](/C=C/C(=O)OCCN(C)C)[C@@]1(C)CCC2C(CC[C@@H]3C[C@@H](O)CC[C@]23C)C1=O | Homo sapiens | CHEMBL751505 | single protein format |
| CHEMBL2068917 |  |
IC50 | = | 350.0 | nM | 376.54 | COC(=O)/C=C/[C@H]1CC[C@]2(O)[C@@H]3CC[C@@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C | Homo sapiens | CHEMBL751505 | single protein format |