3D structures mapped by conservation among orthologs

[ Domain: "Ribonuclease H-like" // HSP70_1st ]

 PyMOL session

[ Domain: "Ribonuclease H-like" // MreB_Mbl_C ]

 PyMOL session

[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

 IC50 CSV    Ki CSV

Only the first 20 rows are shown.

molecule_chembl_id	structure	assay_type	relation	value	unit	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL5410116		IC50	=	700.0	nM	384.51	CC[C@@H](C)[C@H](NC(=O)c1cc2ccccc2[nH]1)C(=O)Nc1nc(C)c(C)s1	Homo sapiens	CHEMBL5321340	single protein format
CHEMBL470334		Ki	<	200.0	nM	556.41	N#Cc1ccc(COC[C@H]2O[C@@H](n3c(NCc4ccc(Cl)c(Cl)c4)nc4c(N)ncnc43)[C@H](O)[C@@H]2O)cc1	Homo sapiens	CHEMBL4417084	single protein format