3D structures mapped by conservation among orthologs

[ Domain: "Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases" // DALR_1,tRNA-synt_1d ]

 PyMOL session

[ Domain: "Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain" // Arg_tRNA_synt_N ]

 PyMOL session

[ Domain: "HUP domains" // tRNA-synt_1d ]

 PyMOL session

 [ Alpha Fold Model ] (go)

 Known binders annotated in ChEMBL

 IC50 CSV

Only the first 20 rows are shown.

molecule_chembl_id	structure	assay_type	relation	value	unit	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL1160244		IC50	=	4.5	nM	502.51	N=C(N)NCCC[C@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	Homo sapiens	CHEMBL645582	single protein format
CHEMBL434782		IC50	=	7.5	nM	489.43	N=C(N)NCCC[C@H](N)COP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	Homo sapiens	CHEMBL645582	single protein format