P54098 | DPOG1_HUMAN | DNA polymerase subunit gamma-1 (POLG)

Pfam Domain Table

AccessionDomainRangeColor
PF18136DNApol_Exo - DNA mitochondrial polymerase exonuclease domain121~414

3D structures mapped by conservation among orthologs

[ Domain: "helical bundle in Bacillus stearothermophilus-like DNA polymerase I" // DNA_pol_A_2nd ]

 PyMOL session

[ Domain: ""fingers" domain in bacteriophage RB69-like DNA polymerase I" // DNA_pol_A_1st ]

 PyMOL session

[ Domain: "Adenylyl and guanylyl cyclase catalytic domain-like" // DNA_pol_A_3rd ]

 PyMOL session

[ Domain: "Ribonuclease H-like" // KOG3657 ]

 PyMOL session


[ Alpha Fold Model ] (go)



Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL483492 IC50 = 500.0 nM 483.18 Cc1cn([C@@H]2C[C@@H](F)[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)nc1N Homo sapiens CHEMBL658102 single protein format