3D structures mapped by conservation among orthologs

[ Domain: "Ribosomal protein S5 domain 2-like" // GHMP_kinases_N_1 ]

 PyMOL session

[ Domain: "GHMP Kinase, C-terminal domain" // KOG2833 ]

 PyMOL session

[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

 IC50 CSV    Ki CSV

Only the first 20 rows are shown.

molecule_chembl_id	structure	assay_type	relation	value	unit	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL1160294		IC50	=	9.0	nM	333.13	O=C(O)[C@@H]1CCCN1C(=O)COP(=O)(O)OP(=O)(O)O	Homo sapiens	CHEMBL714139	single protein format
CHEMBL1160331		IC50	=	15.0	nM	333.13	O=C(O)[C@H]1CCCN1C(=O)COP(=O)(O)OP(=O)(O)O	Homo sapiens	CHEMBL714139	single protein format
CHEMBL1160329		IC50	=	150.0	nM	296.13	O=C(O)CSCCOP(=O)(O)OP(=O)(O)O	Homo sapiens	CHEMBL714139	single protein format
CHEMBL1160332		IC50	=	300.0	nM	307.09	CN(CC(=O)O)C(=O)COP(=O)(O)OP(=O)(O)O	Homo sapiens	CHEMBL713612	single protein format
CHEMBL1160328		Ki	=	37.0	nM	326.11	O=C(O)C[C@@](O)(CF)CCOP(=O)(O)OP(=O)(O)O	Homo sapiens	CHEMBL714140	single protein format
CHEMBL1160330		Ki	=	750.0	nM	293.11	CN(CCOP(=O)(O)OP(=O)(O)O)CC(=O)O	Homo sapiens	CHEMBL714140	single protein format