P52565 | GDIR1_HUMAN | Rho GDP-dissociation inhibitor 1 (ARHGDIA)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02115 | Rho_GDI - RHO protein GDP dissociation inhibitor | 13~201 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // Rho_GDI ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3647977 |  |
Ki | = | 35.0 | nM | 406.53 | Cc1ccc(CN2C3CCC2CC(Nc2ccc4[nH]ncc4c2)C3)cc1OCCO | Homo sapiens | CHEMBL3705256 | single protein format |
| CHEMBL3647976 |  |
Ki | = | 59.0 | nM | 392.5 | OCCOc1cccc(CN2C3CCC2CC(Nc2ccc4[nH]ncc4c2)C3)c1 | Homo sapiens | CHEMBL3705256 | single protein format |
| CHEMBL3647974 |  |
Ki | = | 72.0 | nM | 332.45 | c1ccc(CN2C3CCC2CC(Nc2ccc4[nH]ncc4c2)C3)cc1 | Homo sapiens | CHEMBL3705256 | single protein format |
| CHEMBL3647975 |  |
Ki | = | 91.0 | nM | 346.48 | Cc1ccc(CN2C3CCC2CC(Nc2ccc4[nH]ncc4c2)C3)cc1 | Homo sapiens | CHEMBL3705256 | single protein format |
| CHEMBL3647978 |  |
Ki | = | 806.0 | nM | 343.47 | c1ccc(CN2C3CCC2CC(Nc2cccc4cnccc24)C3)cc1 | Homo sapiens | CHEMBL3705256 | single protein format |
| CHEMBL3647979 |  |
Ki | = | 976.0 | nM | 318.42 | c1ccc(CN2CC3CCC2C3Nc2ccc3[nH]ncc3c2)cc1 | Homo sapiens | CHEMBL3705256 | single protein format |