P51817 | PRKX_HUMAN | cAMP-dependent protein kinase catalytic subunit PRKX (PRKX)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 51~303 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 1.39 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328584 | single protein format |
| CHEMBL494089 |  |
IC50 | = | 5.0 | nM | 425.49 | CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)ncc(OC[C@H]3CCCNC3)c21 | Homo sapiens | CHEMBL1028111 | single protein format |
| CHEMBL4872886 |  |
IC50 | = | 326.0 | nM | 339.34 | CC(C)C[C@@H](N)C(=O)Nc1ccc(-c2cnco2)c(OC(F)F)c1 | Homo sapiens | CHEMBL4829170 | assay format |
| CHEMBL2334586 |  |
IC50 | = | 580.0 | nM | 332.41 | CC(C)(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 | Homo sapiens | CHEMBL5111456 | assay format |
| CHEMBL583144 |  |
Ki | = | 584.7 | nM | 271.13 | O=c1[nH]cnc2c1sc1c(Cl)ccc(Cl)c12 | Homo sapiens | CHEMBL1060318 | single protein format |