P51686 | CCR9_HUMAN | C-C chemokine receptor type 9 (CCR9)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 65~317 |
3D structures mapped by conservation among orthologs
[ Domain: "Family A G protein-coupled receptor-like" // 7tm_1_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2178578 |  |
IC50 | = | 6.0 | nM | 444.94 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2cc[n+]([O-])cc2)cc1 | Homo sapiens | CHEMBL2184877 | single protein format |
| CHEMBL3604486 |  |
IC50 | = | 23.0 | nM | 416.93 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2nccnc2N)cc1 | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3604487 |  |
IC50 | = | 23.0 | nM | 416.93 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2nnccc2N)cc1 | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3604489 |  |
IC50 | = | 30.0 | nM | 432.93 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2nc(N)ncc2O)cc1 | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3604499 |  |
IC50 | = | 34.0 | nM | 460.99 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2nccnc2NCCO)cc1 | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3604496 |  |
IC50 | = | 60.0 | nM | 445.97 | CCc1ncnc(-c2cc(Cl)ccc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1O | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3604493 |  |
IC50 | = | 105.0 | nM | 460.99 | CN(C)c1ncnc(-c2cc(Cl)ccc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1O | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3604494 |  |
IC50 | = | 190.0 | nM | 502.04 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2nncc(N3CCOCC3)c2N)cc1 | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3814811 |  |
IC50 | = | 218.0 | nM | 372.85 | COCC(C)(C)c1ccc(Cn2c(C(=O)O)cc3ncc(Cl)cc32)cc1 | Homo sapiens | CHEMBL3815318 | cell-based format |
| CHEMBL3604497 |  |
IC50 | = | 235.0 | nM | 430.96 | CNc1nccnc1-c1cc(Cl)ccc1NS(=O)(=O)c1ccc(C(C)(C)C)cc1 | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3814736 |  |
IC50 | = | 277.0 | nM | 342.83 | CC(C)(C)c1ccc(Cn2c(C(=O)O)cc3ncc(Cl)cc32)cc1 | Homo sapiens | CHEMBL3815318 | cell-based format |
| CHEMBL3604495 |  |
IC50 | = | 325.0 | nM | 447.94 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2ncnc(CO)c2O)cc1 | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3604483 |  |
IC50 | = | 330.0 | nM | 446.96 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2nccc(CO)c2O)cc1 | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3604492 |  |
IC50 | = | 340.0 | nM | 432.93 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2ncnc(N)c2O)cc1 | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3814251 |  |
IC50 | = | 590.0 | nM | 354.71 | O=C(O)c1cc2ncc(Cl)cc2n1Cc1ccc(C(F)(F)F)cc1 | Homo sapiens | CHEMBL3815318 | cell-based format |
| CHEMBL3604488 |  |
IC50 | = | 750.0 | nM | 417.92 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2ncncc2O)cc1 | Homo sapiens | CHEMBL3607107 | single protein format |
| CHEMBL3799487 |  |
Ki | = | 3.0 | nM | 499.98 | COc1ccncc1N1C(=O)c2c(Cl)ccc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C1=O | Homo sapiens | CHEMBL3801237 | cell-based format |
| CHEMBL3798612 |  |
Ki | = | 9.0 | nM | 469.95 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)c3c2C(=O)N(c2ccccn2)C3=O)cc1 | Homo sapiens | CHEMBL3801237 | cell-based format |
| CHEMBL2178578 | |
Ki | = | 10.0 | nM | 444.94 | CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2C(=O)c2cc[n+]([O-])cc2)cc1 | Homo sapiens | CHEMBL3801237 | cell-based format |
| CHEMBL3800062 |  |
Ki | = | 14.0 | nM | 483.98 | Cc1ncccc1N1C(=O)c2c(Cl)ccc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C1=O | Homo sapiens | CHEMBL3801237 | cell-based format |