P50570 | DYN2_HUMAN | Dynamin-2 (DNM2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00169 | PH - PH domain | 520~621 | |
| PF00350 | Dynamin_N - Dynamin family | 34~207 | |
| PF01031 | Dynamin_M - Dynamin central region | 215~501 | |
| PF02212 | GED - Dynamin GTPase effector domain | 650~738 |
3D structures mapped by conservation among orthologs
[ Domain: "PH domain-like" // PH ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1094197 |  |
IC50 | = | 290.0 | nM | 480.43 | N=c1oc2cc(O)c(O)cc2cc1C(=O)NCCCNC(=O)c1cc2cc(O)c(O)cc2oc1=N | Homo sapiens | CHEMBL1110055 | cell-based format |
| CHEMBL1098764 |  |
IC50 | = | 390.0 | nM | 480.43 | N=c1oc2c(O)c(O)ccc2cc1C(=O)NCCCNC(=O)c1cc2ccc(O)c(O)c2oc1=N | Homo sapiens | CHEMBL1110055 | cell-based format |
| CHEMBL1094850 |  |
IC50 | = | 440.0 | nM | 466.41 | N=c1oc2c(O)c(O)ccc2cc1C(=O)NCCNC(=O)c1cc2ccc(O)c(O)c2oc1=N | Homo sapiens | CHEMBL1110055 | cell-based format |