P49842 | STK19_HUMAN | Serine/threonine-protein kinase 19 (STK19)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF10494 | Stk19 - Inactive serine-threonine protein kinase 19 | 53~251 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4870304 |  |
IC50 | = | 24.04 | nM | 499.53 | COc1cc2nc(NC3CC3)nc(NC3CCN(C(C)C)CC3)c2cc1OC.O=C(O)C(F)(F)F | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4866963 |  |
IC50 | = | 29.33 | nM | 342.4 | COc1cc2nc(-c3ccccc3)nc(-c3ccccc3)c2cc1OC | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4852690 |  |
IC50 | = | 48.32 | nM | 503.52 | CC(C)N1CCC(Nc2nc(N3CCC(F)(F)CC3)nc3ccccc23)CC1.O=C(O)C(F)(F)F | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4849486 |  |
IC50 | = | 57.12 | nM | 407.47 | COc1cc2nc(N3CCN(C)CC3)nc(N3CCC(F)(F)CC3)c2cc1OC | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4852751 |  |
IC50 | = | 64.55 | nM | 385.41 | COc1cc2nc(N3CCC(F)(F)CC3)nc(-c3ccccc3)c2cc1OC | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4850497 |  |
IC50 | = | 70.01 | nM | 395.45 | COc1cc2nc(N3CCC(F)(F)CC3)nc(NCCN(C)C)c2cc1OC | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4845829 |  |
IC50 | = | 79.04 | nM | 325.46 | CC(C)N1CCC(Nc2nc(NC3CC3)nc3ccccc23)CC1 | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4867099 |  |
IC50 | = | 79.88 | nM | 521.49 | COc1cc2nc(N3CCC(F)(F)CC3)nc(N3CCN(C)CC3)c2cc1OC.O=C(O)C(F)(F)F | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4861911 |  |
IC50 | = | 90.91 | nM | 542.6 | COc1cc2nc(N3CCN(C)CC3)nc(NC3CCN(C(C)C)CC3)c2cc1OC.O=C(O)C(F)(F)F | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4865989 |  |
IC50 | = | 96.67 | nM | 406.53 | COc1cc2nc(-c3ccccc3)nc(NC3CCN(C(C)C)CC3)c2cc1OC | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4854631 |  |
IC50 | = | 98.77 | nM | 492.45 | COc1cc2nc(N3CCC(F)(F)CC3)nc(NC3CCC3)c2cc1OC.O=C(O)C(F)(F)F | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4866469 |  |
IC50 | = | 101.7 | nM | 542.45 | COc1cc2nc(N3CCC(F)(F)CC3)nc(N3CCC(F)(F)CC3)c2cc1OC.O=C(O)C(F)(F)F | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4853823 |  |
IC50 | = | 127.2 | nM | 416.57 | COc1cc2nc(NCCN(C)C)nc(NC3CCN(C(C)C)CC3)c2cc1OC | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4869170 |  |
IC50 | = | 137.0 | nM | 514.45 | COc1cc2nc(N3CCC(F)(F)CC3)nc(Nc3ccccc3)c2cc1OC.O=C(O)C(F)(F)F | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4863409 |  |
IC50 | = | 148.3 | nM | 563.57 | COc1cc2nc(N3CCC(F)(F)CC3)nc(NC3CCN(C(C)C)CC3)c2cc1OC.O=C(O)C(F)(F)F | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4852657 |  |
IC50 | = | 178.2 | nM | 401.56 | CCC(C)Nc1nc(NC2CCN(C(C)C)CC2)c2cc(OC)c(OC)cc2n1 | Homo sapiens | CHEMBL4805274 | single protein format |
| CHEMBL4865317 |  |
IC50 | = | 251.9 | nM | 399.54 | COc1cc2nc(N(C)C3CC3)nc(NC3CCN(C(C)C)CC3)c2cc1OC | Homo sapiens | CHEMBL4805274 | single protein format |