P49798 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00615 | RGS - Regulator of G protein signaling domain | 62~177 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2037351 |  |
IC50 | = | 5.4 | nM | 332.81 | Cc1ccc(-n2sc(=O)n(Cc3ccc(Cl)cc3)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037350 |  |
IC50 | = | 7.2 | nM | 312.39 | Cc1ccc(Cn2sc(=O)n(Cc3ccccc3)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037352 |  |
IC50 | = | 8.6 | nM | 312.39 | Cc1ccc(Cn2c(=O)sn(-c3ccc(C)cc3)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037229 |  |
IC50 | = | 10.9 | nM | 332.36 | COc1ccc(-n2sc(=O)n(Cc3ccc(F)cc3)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037234 |  |
IC50 | = | 12.9 | nM | 330.38 | Cc1ccc(Cn2sc(=O)n(Cc3ccc(F)cc3)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037228 |  |
IC50 | = | 13.5 | nM | 336.77 | O=c1sn(-c2ccc(Cl)cc2)c(=O)n1Cc1ccc(F)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037365 |  |
IC50 | = | 14.0 | nM | 264.35 | Cc1ccc(-n2sc(=O)n(CC(C)C)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL24773 |  |
IC50 | = | 14.4 | nM | 202.28 | CCCCn1c(=O)sn(CC)c1=O | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037235 |  |
IC50 | = | 14.4 | nM | 298.37 | Cc1ccc(-n2sc(=O)n(Cc3ccccc3)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037354 |  |
IC50 | = | 14.5 | nM | 312.39 | Cc1ccc(-n2sc(=O)n(Cc3cccc(C)c3)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2035006 |  |
IC50 | = | 15.6 | nM | 282.34 | CCCCn1sc(=O)n(Cc2ccc(F)cc2)c1=O | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037227 |  |
IC50 | = | 16.3 | nM | 302.33 | O=c1sn(-c2ccccc2)c(=O)n1Cc1ccc(F)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037353 |  |
IC50 | = | 17.4 | nM | 332.81 | Cc1ccc(-n2sc(=O)n(Cc3cccc(Cl)c3)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037358 |  |
IC50 | = | 18.9 | nM | 222.27 | Cc1ccc(-n2sc(=O)n(C)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037362 |  |
IC50 | = | 19.7 | nM | 264.35 | CCCCn1c(=O)sn(-c2ccc(C)cc2)c1=O | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037357 |  |
IC50 | = | 22.3 | nM | 254.29 | CCn1sc(=O)n(Cc2ccc(F)cc2)c1=O | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037359 |  |
IC50 | = | 22.3 | nM | 160.2 | CCn1sc(=O)n(C)c1=O | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037360 |  |
IC50 | = | 23.5 | nM | 188.25 | CCCCn1sc(=O)n(C)c1=O | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037236 |  |
IC50 | = | 23.5 | nM | 284.34 | O=c1sn(-c2ccccc2)c(=O)n1Cc1ccccc1 | Homo sapiens | CHEMBL2039222 | single protein format |
| CHEMBL2037238 |  |
IC50 | = | 23.9 | nM | 314.37 | COc1ccc(-n2sc(=O)n(Cc3ccccc3)c2=O)cc1 | Homo sapiens | CHEMBL2039222 | single protein format |