P49789 | FHIT_HUMAN | Bis(5'-adenosyl)-triphosphatase (FHIT)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01230 | HIT | 11–104 |
3D structures mapped by conservation among orthologs
[ Domain: "HIT-related" // HIT ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5083166 |  |
IC50 | = | 49.0 | nM | 434.33 | CC1(C)CC(=O)C2=C(C1)NC1=C(C(=O)c3ccccc31)C2c1ccc(Br)cc1 | Homo sapiens | CHEMBL5033286 | cell-based format |
| CHEMBL5079345 |  |
IC50 | = | 120.0 | nM | 368.18 | O=C(COc1ccc2c3c(c(=O)oc2c1Br)CCCC3)NO | Homo sapiens | CHEMBL5033267 | single protein format |
| CHEMBL5078809 |  |
IC50 | = | 140.0 | nM | 303.31 | Cc1c(OCC(=O)NO)ccc2c3c(c(=O)oc12)CCCC3 | Homo sapiens | CHEMBL5033272 | single protein format |
| CHEMBL5075611 |  |
IC50 | = | 770.0 | nM | 311.3 | CN1C(=O)N/C(=C/c2cccn2-c2ccc(C(=O)O)cc2)C1=O | Homo sapiens | CHEMBL5033267 | single protein format |