P49683 | PRLHR_HUMAN | Prolactin-releasing peptide receptor (PRLHR)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 77~335 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3734012 |  |
Ki | = | 2.0 | nM | 537.52 | CC#CCn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1F)CC2 | Homo sapiens | CHEMBL3887681 | cell-based format |
| CHEMBL3731943 |  |
Ki | = | 2.0 | nM | 497.48 | COn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1)CC2 | Homo sapiens | CHEMBL3734209 | cell-based format |
| CHEMBL3733288 |  |
Ki | = | 2.0 | nM | 573.98 | CC#CCn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1F)CC2.Cl | Homo sapiens | CHEMBL3734209 | cell-based format |
| CHEMBL3728036 |  |
Ki | = | 2.0 | nM | 537.52 | C#CCCn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1F)CC2 | Homo sapiens | CHEMBL3734209 | cell-based format |
| CHEMBL3899144 |  |
Ki | = | 2.0 | nM | 497.48 | COn1c(NC(C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1)CC2 | Homo sapiens | CHEMBL3887681 | cell-based format |
| CHEMBL3734028 |  |
Ki | = | 3.0 | nM | 495.99 | COn1c(N[C@@H](C)c2ccc(Cl)cc2)nc2c(c1=O)CN(C(=O)c1cc3cccnc3s1)CC2 | Homo sapiens | CHEMBL3887681 | cell-based format |
| CHEMBL3731703 |  |
Ki | = | 3.0 | nM | 532.45 | COn1c(N[C@@H](C)c2ccc(Cl)cc2)nc2c(c1=O)CN(C(=O)c1cc3cccnc3s1)CC2.Cl | Homo sapiens | CHEMBL3734209 | cell-based format |
| CHEMBL3964982 |  |
Ki | = | 3.0 | nM | 570.55 | CC(Nc1nc2c(c(=O)n1N1CCOCC1)CN(C(=O)c1ccc(C#N)cc1F)CC2)c1ccc(C(F)(F)F)cc1 | Homo sapiens | CHEMBL3887681 | cell-based format |
| CHEMBL3909684 |  |
Ki | = | 4.0 | nM | 500.52 | COn1c(NC(C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C)c(C)c1)CC2 | Homo sapiens | CHEMBL3887681 | cell-based format |
| CHEMBL3729468 |  |
Ki | = | 4.0 | nM | 500.52 | COn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C)c(C)c1)CC2 | Homo sapiens | CHEMBL3734209 | cell-based format |
| CHEMBL3730970 |  |
Ki | = | 5.0 | nM | 559.95 | C#CCn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1F)CC2.Cl | Homo sapiens | CHEMBL3734209 | cell-based format |
| CHEMBL3734004 |  |
Ki | = | 5.0 | nM | 523.49 | C#CCn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1F)CC2 | Homo sapiens | CHEMBL3887681 | cell-based format |
| CHEMBL3729087 |  |
Ki | = | 5.0 | nM | 529.49 | CCOn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1F)CC2 | Homo sapiens | CHEMBL3734209 | cell-based format |
| CHEMBL4114820 |  |
Ki | = | 5.0 | nM | 529.49 | CCOn1c(N[C@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1F)CC2 | Homo sapiens | CHEMBL3887681 | cell-based format |
| CHEMBL3729902 |  |
Ki | = | 5.0 | nM | 519.53 | C#CCCn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1)CC2 | Homo sapiens | CHEMBL3734209 | cell-based format |
| CHEMBL3898373 |  |
Ki | = | 5.0 | nM | 520.52 | C#CCCn1c(NN(C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(C#N)cc1)CC2 | Homo sapiens | CHEMBL3887681 | cell-based format |
| CHEMBL3728492 |  |
Ki | = | 6.0 | nM | 575.94 | C[C@H](Nc1nc2c(c(=O)n1N(C)C)CN(C(=O)c1c(F)cc(F)cc1F)CC2)c1ccc(C(F)(F)F)cc1.Cl | Homo sapiens | CHEMBL3734209 | cell-based format |
| CHEMBL3940821 |  |
Ki | = | 6.0 | nM | 540.47 | CN(Nc1nc2c(c(=O)n1N(C)C)CN(C(=O)c1c(F)cc(F)cc1F)CC2)c1ccc(C(F)(F)F)cc1 | Homo sapiens | CHEMBL3887681 | cell-based format |
| CHEMBL3727469 |  |
Ki | = | 6.0 | nM | 527.5 | COn1c(N[C@@H](C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)COc1ccc(C#N)cc1)CC2 | Homo sapiens | CHEMBL3734209 | cell-based format |
| CHEMBL3727434 |  |
Ki | = | 6.0 | nM | 554.55 | C[C@H](Nc1nc2c(c(=O)n1N1CCCC1)CN(C(=O)c1ccc(C#N)cc1F)CC2)c1ccc(C(F)(F)F)cc1 | Homo sapiens | CHEMBL3734209 | cell-based format |