P49116 | NR2C2_HUMAN | Nuclear receptor subfamily 2 group C member 2 (NR2C2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00104 | Hormone_recep - Ligand-binding domain of nuclear hormone receptor | 373~566 | |
| PF00105 | zf-C4 - Double treble clef zinc finger, C4 type | 116~183 |
3D structures mapped by conservation among orthologs
[ Domain: "Nuclear receptor ligand-binding domain" // Hormone_recep_1 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2010872 |  |
IC50 | = | 14.0 | nM | 477.57 | CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 | Homo sapiens | CHEMBL2016118 | single protein format |
| CHEMBL3426225 |  |
IC50 | = | 61.0 | nM | 576.63 | CCn1nc(C#Cc2cc(C(=O)Nc3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)ccc2C)c2c(N)ncnc21 | Homo sapiens | CHEMBL3429880 | single protein format |
| CHEMBL5188433 |  |
IC50 | = | 120.0 | nM | 392.89 | COC(=O)Nc1cc(-c2cnc(OC[C@@](C)(N)CC(C)C)c(Cl)c2)ccn1 | Homo sapiens | CHEMBL5161266 | single protein format |
| CHEMBL5088153 |  |
IC50 | = | 126.0 | nM | 575.07 | Cc1cc(NC(=O)Nc2cc(C(C)(C)C)nn2-c2ccc(Cl)cc2)ccc1Nc1ncnc2c1OC(C)(C)C(=O)N2 | Homo sapiens | CHEMBL5045163 | single protein format |
| CHEMBL5185000 |  |
IC50 | = | 260.0 | nM | 383.45 | COC(=O)Nc1cc(-c2cnc(OC[C@@](C)(N)CC(C)C)c(C#N)c2)ccn1 | Homo sapiens | CHEMBL5161266 | single protein format |