P48169 | GBRA4_HUMAN | Gamma-aminobutyric acid receptor subunit alpha-4 (GABRA4)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02931 | Neur_chan_LBD - Neurotransmitter-gated ion-channel ligand binding domain | 49~256 | |
| PF02932 | Neur_chan_memb - Neurotransmitter-gated ion-channel transmembrane region | 263~538 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL415290 |  |
Ki | = | 0.85 | nM | 319.75 | CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(Cl)ccc1-2 | Homo sapiens | CHEMBL1282598 | single protein format |
| CHEMBL407 |  |
Ki | = | 2.0 | nM | 303.29 | CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(F)ccc1-2 | Homo sapiens | CHEMBL942243 | cell-based format |
| CHEMBL45198 |  |
Ki | = | 27.9 | nM | 386.48 | Cc1csc(-c2cc(-c3ccncc3)c3n(c2=O)CCCc2ccncc2-3)n1 | Homo sapiens | CHEMBL646569 | cell-based format |
| CHEMBL1522 |  |
Ki | = | 102.0 | nM | 388.82 | CN1CCN(C(=O)O[C@H]2c3nccnc3C(=O)N2c2ccc(Cl)cn2)CC1 | Homo sapiens | CHEMBL942243 | cell-based format |
| CHEMBL453066 |  |
Ki | = | 1000.0 | nM | 226.24 | COC(=O)c1cc2c(cn1)[nH]c1ccccc12 | Homo sapiens | CHEMBL5235570 | single protein format |
| CHEMBL454606 |  |
Ki | = | 1000.0 | nM | 240.26 | CCOC(=O)c1cc2c(cn1)[nH]c1ccccc12 | Homo sapiens | CHEMBL5235570 | single protein format |
| CHEMBL509197 |  |
Ki | = | 1000.0 | nM | 268.32 | CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccccc12 | Homo sapiens | CHEMBL5235570 | single protein format |
| CHEMBL499814 |  |
Ki | = | 1000.0 | nM | 226.28 | CCCOc1cc2c(cn1)[nH]c1ccccc12 | Homo sapiens | CHEMBL5235570 | single protein format |
| CHEMBL1270841 |  |
Ki | = | 1000.0 | nM | 316.36 | CC(OC(=O)c1cc2c(cn1)[nH]c1ccccc12)c1ccccc1 | Homo sapiens | CHEMBL5235570 | single protein format |