P48058 | GRIA4_HUMAN | Glutamate receptor 4 (GRIA4)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00060 | Lig_chan - Ligand-gated ion channel | 545~825 | |
| PF01094 | ANF_receptor - Receptor family ligand binding region | 40~381 | |
| PF10613 | Lig_chan-Glu_bd - Ligated ion channel L-glutamate- and glycine-binding site | 416~530 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL370038 |  |
Ki | = | 2.7 | nM | 254.21 | Cn1nnc(-c2onc(O)c2C[C@H](N)C(=O)O)n1 | Homo sapiens | CHEMBL829621 | cell-based format |
| CHEMBL331696 |  |
Ki | = | 3.6 | nM | 234.6 | N[C@@H](Cn1nc(Cl)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL878454 | cell-based format |
| CHEMBL331644 |  |
Ki | = | 7.9 | nM | 279.05 | N[C@@H](Cn1nc(Br)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL878454 | cell-based format |
| CHEMBL121553 |  |
Ki | = | 19.9 | nM | 326.05 | N[C@@H](Cn1nc(I)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL878454 | cell-based format |
| CHEMBL13378 |  |
Ki | = | 40.0 | nM | 186.17 | Cc1onc(O)c1CC(N)C(=O)O | Homo sapiens | CHEMBL696664 | cell-based format |
| CHEMBL370941 |  |
Ki | = | 44.4 | nM | 268.23 | CCn1nnc(-c2onc(O)c2CC(N)C(=O)O)n1 | Homo sapiens | CHEMBL829621 | cell-based format |
| CHEMBL120808 |  |
Ki | = | 89.0 | nM | 214.18 | Cc1nn(C[C@H](N)C(=O)O)c(=O)[nH]c1=O | Homo sapiens | CHEMBL878454 | cell-based format |
| CHEMBL276815 |  |
Ki | = | 155.0 | nM | 186.17 | Cc1onc(O)c1C[C@H](N)C(=O)O | Homo sapiens | CHEMBL878454 | cell-based format |
| CHEMBL429594 |  |
Ki | = | 182.0 | nM | 189.2 | N[C@@H](Cc1nsnc1O)C(=O)O | Homo sapiens | CHEMBL934445 | cell-based format |
| CHEMBL122656 |  |
Ki | = | 189.0 | nM | 200.15 | N[C@@H](Cn1ncc(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL878454 | cell-based format |
| CHEMBL121191 |  |
Ki | = | 207.0 | nM | 244.16 | N[C@@H](Cn1cc([N+](=O)[O-])c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL878454 | cell-based format |
| CHEMBL123132 |  |
Ki | = | 305.0 | nM | 217.16 | N[C@@H](Cn1cc(F)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL878454 | cell-based format |
| CHEMBL121388 |  |
Ki | = | 451.0 | nM | 233.61 | N[C@@H](Cn1cc(Cl)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL878454 | cell-based format |
| CHEMBL333964 |  |
Ki | = | 457.0 | nM | 278.06 | N[C@@H](Cn1cc(Br)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL878454 | cell-based format |
| CHEMBL51660 |  |
Ki | = | 533.0 | nM | 213.23 | N[C@@H](CC(C(=O)O)=C1CCCC1)C(=O)O | Homo sapiens | CHEMBL696661 | cell-based format |
| CHEMBL222519 |  |
Ki | = | 600.0 | nM | 336.29 | NS(=O)(=O)c1cccc2c1c([N+](=O)[O-])cc1nc(O)c(O)nc12 | Homo sapiens | CHEMBL874140 | single protein format |
| CHEMBL372643 |  |
Ki | = | 732.0 | nM | 282.26 | CCCn1nnc(-c2onc(O)c2CC(N)C(=O)O)n1 | Homo sapiens | CHEMBL829621 | cell-based format |
| CHEMBL575060 |  |
Ki | = | 868.0 | nM | 147.13 | N[C@@H](CCC(=O)O)C(=O)O | Homo sapiens | CHEMBL696662 | cell-based format |
| CHEMBL121915 |  |
Ki | = | 972.0 | nM | 325.06 | N[C@@H](Cn1cc(I)c(=O)[nH]c1=O)C(=O)O | Homo sapiens | CHEMBL878454 | cell-based format |