P47211 | GALR1_HUMAN | Galanin receptor type 1 (GALR1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 50~303 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3906195 |  |
IC50 | = | 190.0 | nM | 286.37 | Cc1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3941767 |  |
IC50 | = | 260.0 | nM | 351.24 | O=S1(=O)C=C(c2ccc(Br)cc2)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3955764 |  |
IC50 | = | 371.0 | nM | 322.41 | O=S1(=O)C=C(c2cccc3ccccc23)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3944461 |  |
IC50 | = | 410.0 | nM | 290.34 | O=S1(=O)C=C(c2ccc(F)cc2)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3958445 |  |
IC50 | = | 410.0 | nM | 364.44 | O=S1(=O)C=C(c2ccc(Oc3ccccc3)cc2)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3903219 |  |
IC50 | = | 430.0 | nM | 290.34 | O=S1(=O)C=C(c2ccccc2F)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3943955 |  |
IC50 | = | 430.0 | nM | 300.4 | CCc1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3941717 |  |
IC50 | = | 440.0 | nM | 392.45 | O=C(Oc1ccccc1)c1cccc(C2=CS(=O)(=O)CCCS2(=O)=O)c1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3918646 |  |
IC50 | = | 490.0 | nM | 356.34 | O=S1(=O)C=C(c2ccc(OC(F)(F)F)cc2)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3921852 |  |
IC50 | = | 570.0 | nM | 351.24 | O=S1(=O)C=C(c2ccccc2Br)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3919125 |  |
IC50 | = | 580.0 | nM | 340.34 | O=S1(=O)C=C(c2ccccc2C(F)(F)F)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3905888 |  |
IC50 | = | 590.0 | nM | 316.4 | CCOc1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3891488 |  |
IC50 | = | 600.0 | nM | 348.44 | O=S1(=O)C=C(c2ccc(-c3ccccc3)cc2)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3932833 |  |
IC50 | = | 600.0 | nM | 340.34 | O=S1(=O)C=C(c2cccc(C(F)(F)F)c2)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3906449 |  |
IC50 | = | 640.0 | nM | 306.79 | O=S1(=O)C=C(c2ccccc2Cl)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3920910 |  |
IC50 | = | 710.0 | nM | 398.24 | O=S1(=O)C=C(c2ccc(I)cc2)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3941261 |  |
IC50 | = | 850.0 | nM | 398.24 | O=S1(=O)C=C(c2cccc(I)c2)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3934499 |  |
IC50 | = | 890.0 | nM | 351.24 | O=S1(=O)C=C(c2cccc(Br)c2)S(=O)(=O)CCC1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3979946 |  |
IC50 | = | 910.0 | nM | 302.37 | COc1cccc(C2=CS(=O)(=O)CCCS2(=O)=O)c1 | Homo sapiens | CHEMBL3880098 | single protein format |
| CHEMBL3961540 |  |
IC50 | = | 1000.0 | nM | 477.6 | CCCCOc1ccccc1C(=O)NC(Cc1ccccc1)C1=CS(=O)(=O)CCS1(=O)=O | Homo sapiens | CHEMBL3880098 | single protein format |