P46934 | NEDD4_HUMAN | E3 ubiquitin-protein ligase NEDD4 (NEDD4)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00397 | WW | 612–641 | |
| PF00397 | WW | 769–798 | |
| PF00397 | WW | 842–871 | |
| PF00397 | WW | 894–923 | |
| PF00632 | HECT | 1014–1316 |
3D structures mapped by conservation among orthologs
[ Domain: "WW domain" // WW ]
[ Domain: "C2 domain" // C2_1 ]
[ Domain: "Hect, E3 ligase catalytic domain" // HECT ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3621955 |  |
IC50 | = | 500.0 | nM | 352.42 | Cc1nc2ccccc2nc1SCC(=O)NC(=O)Nc1ccccc1 | Homo sapiens | CHEMBL3626195 | single protein format |
| CHEMBL3621954 |  |
IC50 | = | 500.0 | nM | 445.59 | Cc1nn(-c2ccccc2)c(C)c1NC(=O)CN1CCCC(c2nc3ccccc3s2)C1 | Homo sapiens | CHEMBL3626194 | single protein format |