P46734 | MP2K3_HUMAN | Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 66~325 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3746157 |  |
IC50 | = | 4.0 | nM | 244.28 | NC(=O)c1nc(-c2ccns2)c2ccccn12 | Homo sapiens | CHEMBL3751415 | single protein format |
| CHEMBL3747095 |  |
IC50 | = | 4.0 | nM | 228.25 | CNc1ccc(-c2ccncc2)nc1C(N)=O | Homo sapiens | CHEMBL3751415 | single protein format |
| CHEMBL388978 |  |
IC50 | = | 17.2 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328489 | single protein format |
| CHEMBL3747443 |  |
IC50 | = | 30.0 | nM | 214.23 | NC(=O)c1nc(-c2ccncc2)ccc1N | Homo sapiens | CHEMBL3751415 | single protein format |
| CHEMBL3746484 |  |
IC50 | = | 150.0 | nM | 238.25 | NC(=O)c1nc(-c2ccncc2)c2ccccn12 | Homo sapiens | CHEMBL3751415 | single protein format |