P46095 | GPR6_HUMAN | G-protein coupled receptor 6 (GPR6)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 89~329 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4778540 |  |
Ki | = | 5.5 | nM | 473.52 | CC(=O)N1CCc2nc(N3CCC(Oc4ccc(F)cc4F)CC3)c(N[C@@H]3CCOC3)nc2C1 | Homo sapiens | CHEMBL4742498 | cell-based format |
| CHEMBL3962956 |  |
Ki | = | 6.0 | nM | 473.52 | CC(=O)N1CCc2nc(N3CCC(Oc4ccc(F)cc4F)CC3)c(N[C@H]3CCOC3)nc2C1 | Homo sapiens | CHEMBL4742498 | cell-based format |
| CHEMBL4598390 |  |
Ki | = | 7.0 | nM | 396.45 | Fc1ccc(CN2CCN(c3nc4cnccc4nc3NC3CC3)CC2)c(F)c1 | Homo sapiens | CHEMBL5039200 | cell-based format |
| CHEMBL5093828 |  |
Ki | = | 16.0 | nM | 443.5 | CC(=O)N1C=Cc2nc(N3CCC(Oc4ccc(F)cc4F)CC3)c(NC(C)C)nc2C1 | Homo sapiens | CHEMBL5039200 | cell-based format |