P45974 | UBP5_HUMAN | Ubiquitin carboxyl-terminal hydrolase 5 (USP5)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00443 | UCH | 326–853 | |
| PF02148 | zf-UBP | 199–271 | |
| PF17807 | zf-UBP_var | 16–79 | |
| PF22562 | UBA_7 | 656–702 | |
| PF22562 | UBA_7 | 725–768 |
3D structures mapped by conservation among orthologs
[ Domain: "RuvA-C, UBA, CRAL/TRIO-N, HBS1" // UBA ]
[ Domain: "Cysteine proteinases" // UCH ]
[ Domain: "RING/U-box" // zf-UBP ]
[ Domain: "RING/U-box" // KOG0944 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5278336 |  |
IC50 | = | 800.0 | nM | 437.91 | O=C(O)CNC(=O)c1ccc(S(=O)(=O)N2CCC(c3ccc(Cl)cc3)CC2)cn1 | Homo sapiens | CHEMBL5228934 | assay format |